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CANCER
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What is Cancer? Abnormal cells reproducing out of control.
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Most Common Cancers in US
Males: 1.) Prostate Cancer 2.) Lung Cancer 3.) Colon Cancer 4.) Bladder Cancer 5.) Melanoma’s of the skin Females: 1.) Breast Cancer 4.) Uterine Cancer 5.) Thyroid
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How common is cancer? Approximately 39.6% percent of men and women in the United States will be diagnosed with cancer at some point in their life. (down from 40.4%)
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The number of people living beyond a cancer diagnosis:
14.5 million in 2014 19 million by (estimated)
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In 2016, in the United States: *estimated 1,685,210 new
cases of cancer will be diagnosed *estimated 595,690 people will die from the disease.
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There are more than 100 types of cancer.
Types of cancer are usually named for the organs or tissues where the cancers form Also may be described by the type of cell that formed them.
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Prefixes: Adeno - glands Hepato - liver Melano - dark Osteo - bone
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Skin Cancers Occur when: unrepaired DNA damage to skin cells
ultraviolet radiation from sunshine tanning beds triggers mutations, or genetic defects skin cells to multiply rapidly and form malignant tumors.
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Skin Cancers Approximately 2,000,000 new cases per year
Deaths less than 1000 plus most melanoma patients.
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Carcinomas - Skin (may itch) - Surfaces of organs Ex. Stomach, liver, colon, skin, etc
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Carcinomas Basal cell carcinoma Squamous cell carcinoma Adenocarcinoma
Renal cell carcinoma
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Carcinomas – surface cancers
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Basal Cell Carcinoma This is the most common form of all cancers.
It occurs in cells lining the deepest part of the skin's outer layer. Basal cell carcinomas often look like: Open sores Red patches Pink growths Shiny bumps or scars
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Basal Cells
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Basal Cell Carcinoma
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Squamous Cell Carcinoma
Often shows up on the skin. Can also be found in other parts of the body, such as cells lining: Certain organs Digestive tract Respiratory tract Tends to grow and spread more than basal cell cancers. In rare cases, it may spread to the lymph nodes.
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Squamous Cell Carcinoma
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Melanoma Most dangerous form of skin cancer.
Pigment producing melanocytes Resemble moles Mostly brown or black but can be pink, purple, or white. Kills an estimated 10,130 people in the US annually.
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Melanoma
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Sarcomas Rare cancer Grow in connective tissues
Bone Cartilage Tendons Muscles Nerves Blood vessels More common in kids and young people
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Sarcomas More than 50 types of sarcoma Grouped into two main kinds:
soft tissue sarcoma bone sarcoma, or osteosarcoma 12,000 cases of soft tissue sarcoma and 3,000 cases of bone sarcomas were seen in the U.S. in
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Sarcoma Hard to spot Most often the first sign is a painless lump.
No tests that can find these tumors before they cause symptoms that you notice. Early symptoms, including: Pain off and on in the affected bone, which may be worse at night Swelling, which often starts weeks after the pain A limp, if the sarcoma is in your leg
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Lymphoma Immune System – (lymph glands) Most common in young people
Type of white blood cell – lymphocytes Most common in young people Can be any age 2 Types Hodgkins B-cells and T-cells Non-hodgkins Abnormal type of B-cell, Reed-Sternberg cells How Lymphoma Develops
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Leukemia Cancer of: Mainly affects the white blood cells. 2 types:
bone marrow blood Mainly affects the white blood cells. Produce abnormal ones – don’t function properly 2 types: Acute – fast growing Chronic – slow growing Children under 15; adults over 55
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TUMORS Malignant Benign BIOPSY confirms which one it is - Cancerous
- Invade tissues and spread to other parts of the body (METASTASIS) Benign - Are NOT Cancerous - Usually self-encased and grow, but do not spread around the body. BIOPSY confirms which one it is
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Cancer Cells
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Angiogenesis
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Hyperplasia
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Metastasis
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Detecting Cancer Radiation : X-Rays : CT Scans (CAT Scan) (Tomography)
: Ultra Sounds : MRI Etc.
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Lung Cancer X-Ray CT Scan
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Ultrasound
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TESTS TO DETECT PAP Mammograms PSA Colonoscopy Blood FOBT Urine
Chromosome Test (BRCA gene) Sight Test (Dermatologist) Barium Enema Bone Scan
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Upper G.I (H. pylori)
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PSA Prostate Specific Antigen - Produced by the Prostate Gland
BLOOD TEST (Fairly Inexpensive) some insurances do not cover - High numbers indicate possibility Verify by a Digital Rectal Exam (DRE)
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Colonoscopy
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PAP Test Also called a PAP Smear - Long Q-tip
- Cells examined under the microscope - Other cells grown
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FOBT Fecal Occult Blood Test - Used to detect Colon Cancer
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Mammograms Used to detect Breast Cancer
Males can get it too, just not as common BRCA Genes tumor suppressor genes Chromosome 17
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Chromosome Tests Ex. BRCA 1 or BRCA 2 Genes
Show the liklihood of additional breast cancer ONCOGENES = Genes that turn ON Cancer Tumor Suppressor Genes – Shut OFF Cancer
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Colonoscopy Recommended by age 50 and then every 5 to 10 years later (Obamacare starts at 65) Can be done in clinics or hospital Costs & convenience & pain differences
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CAUSES OF CANCER Tobacco Alcohol Drugs Air Pollution Water Pollution
Chemicals Age Heredity Hyperplasia Hormones Carcinogens Diet Obesity Radiation – Including Radon Sunlight
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STAGES OF CANCER STAGE I STAGE II STAGE III STAGE IV
Some actually have a stage 0
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PREVENTION: Avoid the causes Get tested Eat Healthy Exercise
Vaccines (Hepatitus, HPV, +?) Gardasil
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TREATMENTS CHEMO (Chemical Therapy) Radiation
Surgery\Mastectomy\Lumpectomy Hysterectomy, etc. Bone Marrow transplants Stem Cells? Genetic Screening/Testing Clinical Trials Immunotherapy
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Chemotherapy
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Radiation
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Radiation – pin point
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Surgery
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Cancer Cells
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