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Synchronous Metastatic Clear-Cell Renal Cell Carcinoma: A Distinct Morphologic, Immunohistochemical, and Molecular Phenotype  Solene-Florence Kammerer-Jacquet,

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Presentation on theme: "Synchronous Metastatic Clear-Cell Renal Cell Carcinoma: A Distinct Morphologic, Immunohistochemical, and Molecular Phenotype  Solene-Florence Kammerer-Jacquet,"— Presentation transcript:

1 Synchronous Metastatic Clear-Cell Renal Cell Carcinoma: A Distinct Morphologic, Immunohistochemical, and Molecular Phenotype  Solene-Florence Kammerer-Jacquet, Angelique Brunot, Adelaide Pladys, Guillaume Bouzille, Julien Dagher, Sarah Medane, Benoit Peyronnet, Romain Mathieu, Gregory Verhoest, Karim Bensalah, Julien Edeline, Brigitte Laguerre, Alexandra Lespagnol, Jean Mosser, Frederic Dugay, Marc-Antoine Belaud-Rotureau, Nathalie Rioux-Leclercq  Clinical Genitourinary Cancer  Volume 15, Issue 1, Pages e1-e7 (February 2017) DOI: /j.clgc Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 Pathologic Parameters Associated With Synchronous Metastatic Clear Cell Renal Cell Carcinoma (m-ccRCC). A, Sarcomatoid Component, Hematoxylin and Eosin Stain × 200. B, Diffuse Cytoplasmic Expression of Vascular Endothelial Growth Factor a (VEGF-A), Immunohistochemistry (IHC) × 200. C, Cytoplasmic and Membranous Expression of Partitioning-Defective 3 (PAR-3), IHC × 200. D, Programmed Death Ligand 1 (PD-L1) Overexpression With Intense Membranous Staining, IHC × 200 Clinical Genitourinary Cancer  , e1-e7DOI: ( /j.clgc ) Copyright © 2016 Elsevier Inc. Terms and Conditions

3 Figure 2 Cancer-Specific Survival in Patients From Metastasis Diagnosis according to Metastatic Status Abbreviation: m-ccRCC = metastatic clear cell renal cell carcinoma. Clinical Genitourinary Cancer  , e1-e7DOI: ( /j.clgc ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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