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Organic solute transporter (OSTα-OSTβ) expression in human control livers and patients with stage III and IV primary biliary cirrhosis. Organic solute.

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Presentation on theme: "Organic solute transporter (OSTα-OSTβ) expression in human control livers and patients with stage III and IV primary biliary cirrhosis. Organic solute."— Presentation transcript:

1 Organic solute transporter (OSTα-OSTβ) expression in human control livers and patients with stage III and IV primary biliary cirrhosis. Organic solute transporter (OSTα-OSTβ) expression in human control livers and patients with stage III and IV primary biliary cirrhosis. Note that both the α- and β-subunits are significantly increased both at the mRNA (A) and protein levels (B), although much larger increases in expression are observed for the β-subunit. All data represent fold changes in mRNA expression after normalizing control values to 1 (n = 4–6). Control vs. primary biliary cirrhosis (PBC): *P < 0.001, #P < 0.01, +P < 0.05. James L. Boyer et al. Am J Physiol Gastrointest Liver Physiol 2006;290:G1124-G1130 ©2006 by American Physiological Society


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