1. How does DNA copy itself?

2. REPLICATION Replication: DNA copies itself
Each strand of DNA has the information needed to reconstruct the other half
Happens in INTERPHASE
Mitosis
Meiosis

3. REPLICATION
Semiconservative Replication:

4. STEP 1: Unwinding
DNA Helicase: enzyme that unzips DNA

5. STEP 2: Base Pairing
DNA Polymerase: enzyme that adds new nucleotides to DNA half

6. STEP 2: Base Pairing
Leading strand: Built in same directions as DNA unzips (3’5’)

7. STEP 2: Base Pairing
Lagging strand: Built in opposite direction as DNA unzips (3’5’)

8. STEP 2: Base Pairing
Okazaki fragments: pieces of the lagging strand

9. STEP 2: Base Pairing
DNA ligase: joins Okazaki fragments together

10. STEP 3: Joining Replication happens in many places on DNA at once
DNA ligase joins them together

11. Complimentary Base Pairing
Template Strand: The original strand of DNA that is used to make the new copy.

14. Animations Replication Process