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Determination of ketamine and norketamine in hair by micropulverized extraction and liquid chromatography–high resolution mass spectrometry  Donata Favretto,

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Presentation on theme: "Determination of ketamine and norketamine in hair by micropulverized extraction and liquid chromatography–high resolution mass spectrometry  Donata Favretto,"— Presentation transcript:

1 Determination of ketamine and norketamine in hair by micropulverized extraction and liquid chromatography–high resolution mass spectrometry  Donata Favretto, Susanna Vogliardi, Giulia Stocchero, Alessandro Nalesso, Marianna Tucci, Claudio Terranova, Santo Davide Ferrara  Forensic Science International  Volume 226, Issue 1, Pages (March 2013) DOI: /j.forsciint Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

2 Fig. 1 HPLC–HRMS chromatograms obtained for MH+ ions of KT (at m/z ), NK (at m/z ) and IS (at m/z ) from hair spiked at 0.5ng/mg (a and b), true positive hair (c and d) and blank hair (e and f). Forensic Science International  , 88-93DOI: ( /j.forsciint ) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

3 Fig. 2 HPLC–HRMS chromatograms and high resolution isotope clusters obtained for MH+ ions of KT (a), NK (b) and IS (c), from Case 1. Forensic Science International  , 88-93DOI: ( /j.forsciint ) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

4 Supplementary Fig. 1 HRMS/MS spectrum obtained by collision of MH+ ions of KT at m/z 238. Forensic Science International  , 88-93DOI: ( /j.forsciint ) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

5 Supplementary Fig. 2 HRMS/MS spectrum obtained by collision of MH+ ions of NK at m/z 224. Forensic Science International  , 88-93DOI: ( /j.forsciint ) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions


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