1. Dr Ousmane Sarr WANETAM
The West African Network of Excellence for TB, AIDS and Malaria: An Example of sub-regional Collaboration
Dr Ousmane Sarr
WANETAM
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2. Background (1)
HIV, TB, & malaria considered as poverty associated diseases
Constitute major sources of morbidity & mortality in Africa with:
majority of the HIV cases
> 30% of TB cases & TB-HIV co-infections
vast majority of malaria cases and malaria-related deaths
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3. Background (2) West-African sub-region characterized by:
Absence in conducting clinical trials of potential HIV vaccines and/or microbicides
Poverty or lack of data on drug resistant Mycobacterium tuberculosis
Ongoing clinical trials for malaria vaccine candidates in Mali and Burkina Faso
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4. Background (3) West-African sub-region characterized by:
Many research institutions working in isolation or following colonial links
Lack of critical mass of qualified personnel
Inability to attract significant fundings
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5. WANETAM Partnership
7 West-African countries (Burkina Faso, The Gambia, Ghana, Guinea Bissau, Mali, Nigeria, and Senegal)
Bring together scientists from anglophone, francophone and lusophone countries in West Africa.
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7. Objectives
Capacity building and technology transfer to prepare West African institutions for the successful conduct of clinical trials.
Creation of a network for sub- regional scientific collaborations: to facilitate and expedite the development of trial-specific expertise
To this extent, established west-African institutions will help prepare sister institutions for the conduct of CT
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8. Established Institutions
Burkina Faso
B. F Centre MURAZ
G-B, BANDIM
B. F CNRFP
Sister Institutions
The Gambia NPHL
Senegal, LBV
N. Ibadan, COL.M
Gh. NMIMR
N. Keffi Inn.B
Gh. KORLEBU
N. Lagos NIMR
Senegal, IPD
HIV TB
Malaria
Bioethics, GCP, GCLP, Quality control, Writing grant applications, Trial monitoring
Disease
Coordinators
Le Dantec Senegal
MRC- the Gambia
MRTC- Mali &
Burkina Faso CNRFP
Established Institutions
Project
Coordinator
Le Dantec University Senegal
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9. Activities
The main activities of WANETAM are divided into 6 work packages:
WP 1: Project management
WP 2: Training
WP 3: Networking
WP 4: HIV-related lab training and surveys
WP 5: TB-related lab training and surveys
WP 6: Malaria-related lab training and surveys
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10. Governance body Project Coordinator Advisory Board Steering Committee
Manager
HIV DC
TB DC
Malaria DC
Training Adv.
Committee
To be successful, the management is key
Project
Secrétariat
HIV Partners
TB Partners
Malaria Partners
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11. HIV TB Malaria TRAININGS Le Dantec University- Senegal
Molecular virology
HIV resistance typing
Assay standardization
TRAININGS
HIV
CROSS CUTTING
Bioethics
GCP
GCLP
Quality control
Writing grant applications
Trial monitoring
MRTC- Mali/ CNRFP-BF
Malaria specific techniques
Molecular biology –
Haplotyping of parasites
Drug-resistant mutations
New diagnostic tools
Malaria Immunology TB
MRC- the Gambia
Conventional and molecular TB diagnostics and drug susceptibility testing
Malaria
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12. Achievements (1) Cross-cutting trainings Disease-specific trainings
Ethics in clinical research, January, 2011
Data management and GCP, March 2011
Data analysis and grant writing, April 2011
Good Clinical and Lab Practices, May, 2011
Disease-specific trainings
HIV Drug resistance, March 2011
TB Diagnostics & DST, January to February 2011
Malaria Diagnostics, November 2010
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14. Achievements (2)
In total, 185 junior and senior scientists have received clinical trials-associated trainings increasing the critical mass of qualified personnel
Lab and/or infrastructure upgrade have been carried out in Ghana, Guinea-Bissau, Burkina Faso, Nigeria and Senegal
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16. Networking
For sustainability purposes , some institutions have jointly submitted grant proposals:
WAPHIR
WANETAM +
FP7 call
Tri Lateral Initiative
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17. Communication Strategy
Basecamp: is a web-based platform in which partners share information that are of interest for the Network.
Voice on IP: is a new teleconference system allowing free communications between the WANETAM partners
Creation of a website:
Newsletters
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18. Basecamp
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19. Telephony over Internet Protocol
WANETAM Netcentrex
Communications sur IP
Telephony over Internet Protocol
By WAVCOM TECHNOLOGY -
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20. WANETAM Institution Le Dantec (Senegal)
Local Network
GSM Network
World Wide Web
WANETAM Institution
Le Dantec (Senegal)
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21. Conclusions increase of the critical mass of qualified personnel
Infrastructural upgrade in most institutions
Harmonization of protocoles in progress
Sub-regional scientific collaboration is a reality
WAPHIR, WANETAM +
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22. Acknowledgements WANETAM partner institutions EDCTP
NACCAP (the Dutch contribution to EDCTP)
MRC, The UK
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