1. The DMDG In-Vitro Technology Training Course
Day 1
Delegate Arrival and Registration
Course Introduction
Drug Metabolism and Phase I
15: Phase II Enzymes
15: Coffee
Introduction to Transporters
Tutorial 1 (Routes of ADME)
18.30 – 20:00 Dinner
20:00 – 23:00 Quiz
Day 2
Hepatocytes
09: Sub cellular fractions
Coffee
Enzyme Kinetics & Clearance
Tutorial 2 (Enzyme Kinetics)
Lunch
Molecular Methods
Transporter Phenotyping
Coffee
15:45 – 17:30 Tutorial 3 (Clearance & Transporters)
19.00 Dinner + Free evening
Day 3
Inhibition of ADME
09: Induction of ADME
10: Coffee
Tutorial 4 (ADME Inhibition & Induction)
12: Lunch
In Vitro – In Vivo extrapolation
Applications of In Vitro
Coffee
Tutorial 5 intro
15.45 – Tutorial 5
17.45 – Tutorial 5 – Discussion/presentation
20.00 Course Dinner
Day 4
09.00 Delegates Depart
*In the event of oversubscription, places will be allocated according to DMDG rules.