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The Tissue Level of Organization
Group of similar cells common function Histology study of tissues Tortora & Grabowski 9/e 2000 JWS
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4 Basic Types of Tissues Epithelial Connective Muscle Nervous
Tortora & Grabowski 9/e 2000 JWS
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4 Basic Tissues 1. Epithelial Tissue covers surfaces
lines hollow organs, cavities and ducts forms glands Tortora & Grabowski 9/e 2000 JWS
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Epithelial Tissue -- General Features
Closely packed cells Avascular---without blood vessels nutrients diffuse in from underlying connective tissue Good nerve supply Rapid cell division Tortora & Grabowski 9/e 2000 JWS
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Basement Membrane holds epithelial cells to connective tissue
Tortora & Grabowski 9/e 2000 JWS
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Classification of Epithelium
simple = one cell layer thick stratified = many cell layers thick pseudostratified = single layer of cells where all cells don’t reach surface Tortora & Grabowski 9/e 2000 JWS
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cuboidal = cube-shaped columnar = tall column
squamous =flat cuboidal = cube-shaped columnar = tall column transitional = shape varies with tissue stretching Tortora & Grabowski 9/e 2000 JWS
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Simple Squamous Epithelium
Single layer of flat cells found in blood vessels and air sacs in respiratory system very thin --- controls diffusion, osmosis and filtration Tortora & Grabowski 9/e 2000 JWS
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Examples of Simple Squamous
Section of intestinal Surface view of lining of peritoneal cavity Tortora & Grabowski 9/e 2000 JWS
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Simple Cuboidal Epithelium
Single layer of cube-shaped cells Lines the tubes of the kidney Absorption or secretion Tortora & Grabowski 9/e 2000 JWS
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Example of Simple Cuboidal
Sectional view of kidney tubules Tortora & Grabowski 9/e 2000 JWS
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Nonciliated Simple Columnar
Single layer rectangular cells goblet cells - secrete mucus (lubricate) Microvilli = fingerlike cytoplasmic projections for absorption in digestive system(stomach to anus) Tortora & Grabowski 9/e 2000 JWS
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Ex. Nonciliated Simple Columnar
Section from small intestine Tortora & Grabowski 9/e 2000 JWS
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Pseudostratified Columnar
Single cell layer Not all cells reach the surface Goblet cells: mucus traps foreign particles Respiratory system Tortora & Grabowski 9/e 2000 JWS
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Stratified Squamous Epithelium
Several cell layers thick Surface cells flat Keratinized = surface cells dead and filled with keratin skin (epidermis) Nonkeratinized = no keratin in moist living cells at surface mouth, vagina Tortora & Grabowski 9/e 2000 JWS
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Example of Stratified Squamous
Section of vagina Tortora & Grabowski 9/e 2000 JWS
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Papanicolaou Smear (Pap smear)
Collect sloughed off cells of uterus and vaginal walls Detect cellular changes (precancerous cells) Annually for women over 18 or if sexually active Tortora & Grabowski 9/e 2000 JWS
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Stratified Columnar Epithelium
Multilayered Surface cells columnar Rare (very large ducts & part of male urethra) Tortora & Grabowski 9/e 2000 JWS
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Transitional Epithelium
Multilayered Allows tissue to expand and contract Lines hollow organs that expand from within (urinary bladder) Tortora & Grabowski 9/e 2000 JWS
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Glandular Epithelium **Made of cuboidal cells
Exocrine glands cells that secrete---sweat, ear wax, saliva, digestive enzymes through ducts Ex: saliva travels to the oral cavity through ducts Endocrine glands secrete hormones into the bloodstream Tortora & Grabowski 9/e 2000 JWS
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Duct of Multicellular Glands
Sweat gland duct Stratified cuboidal epithelium Tortora & Grabowski 9/e 2000 JWS
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Modes of Glandular Secretion (How glands secrete the “stuff” they make)
Merocrine -- most glands cells release their products by exocytosis---saliva, digestive enzymes & sweat Tortora & Grabowski 9/e 2000 JWS
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whole cells die & rupture to release their products
Holocrine -- oil gland whole cells die & rupture to release their products Tortora & Grabowski 9/e 2000 JWS
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Most abundant type of tissue supports and binds structures together
2. Connective Tissue Most abundant type of tissue supports and binds structures together stores energy as fat provides immunity to disease Tortora & Grabowski 9/e 2000 JWS
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Connective Tissues Cells rarely touch
Matrix: substance surrounding cells liquid, gel or solid Good nerve & blood supply except cartilage & tendons Tortora & Grabowski 9/e 2000 JWS
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Reticular Connective Tissue
Holds organ together (liver, spleen, lymph nodes, bone marrow) Tortora & Grabowski 9/e 2000 JWS
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Elastic Connective Tissue
Can stretch & still return to original shape Lung tissue, vocal cords, ligament between vertebrae Tortora & Grabowski 9/e 2000 JWS
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Adipose Tissue Cell contains large fat storage droplet
Deeper layer of skin, organ padding, yellow marrow Reduces heat loss, energy storage, protection Tortora & Grabowski 9/e 2000 JWS
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Areolar Connective Tissue
Cell types = fibroblasts, plasma cells, macrophages, mast cells and a few white blood cells Tortora & Grabowski 9/e 2000 JWS
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Areolar Connective Tissue
Made of elastin and collagen fibers Found under skin Tortora & Grabowski 9/e 2000 JWS
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Dense Fibrous Connective Tissue
White, tough and pliable (forms tendons) Also known as white fibrous connective tissue Tortora & Grabowski 9/e 2000 JWS
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Blood Cell types = red blood cells (erythrocytes), white blood cells (leukocytes) and cell fragments called platelets Provide clotting, immune functions, carry O2 and CO2 Tortora & Grabowski 9/e 2000 JWS
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Compact Bone (Osseous Tissue)
Osteon = lamellae (rings) of mineralized matrix calcium & phosphate---give it its hardness interwoven collagen fibers provide strength Osteocytes in spaces (lacunae) in between lamellae Tortora & Grabowski 9/e 2000 JWS
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Hyaline Cartilage No blood vessels or nerves so repair is very slow
Located between joints, larynx, trachea, bronchi, nose Tortora & Grabowski 9/e 2000 JWS
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Elastic Cartilage Elastic fibers help maintain shape after deformations Ear, nose, vocal cartilages Tortora & Grabowski 9/e 2000 JWS
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Fibrocartilage Many more collagen fibers causes rigidity & stiffness
Strongest type of cartilage (intervertebral discs) Tortora & Grabowski 9/e 2000 JWS
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Growth & Repair of Cartilage
Grows and repairs slowly because is avascular Tortora & Grabowski 9/e 2000 JWS
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4 Basic Tissues 3. Muscle Tissue cells have the ability to contract
Provide us with motion, posture and heat 4. Nerve Tissue cells that conduct electrical signals detects changes inside and outside the body and responds with nerve impulses Tortora & Grabowski 9/e 2000 JWS
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Smooth Muscle Walls of hollow organs (blood vessels, GI tract, bladder) Involuntary and nonstriated Tortora & Grabowski 9/e 2000 JWS
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Cardiac Muscle Cells are branched cylinders with one central nuclei
Involuntary and striated Tortora & Grabowski 9/e 2000 JWS
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Skeletal Muscle Visible light and dark banding (striated)
Voluntary or conscious control Tortora & Grabowski 9/e 2000 JWS
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Nerve Tissue Cell types – neurons and neuroglial (supporting) cells
Nerve cell (neuron) structure nucleus & long cell processes conduct nerve signals dendrite --- signal travels towards the cell body axon ---- signal travels away from cell body Tortora & Grabowski 9/e 2000 JWS
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Why does cartilage heal so slowly?
Bellringer Why does cartilage heal so slowly? What kind of tissue is found in the skin? Give two examples of connective tissue. What are the 3 types of muscle tissue? What makes nervous tissue unique? Tortora & Grabowski 9/e 2000 JWS
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Read and take notes about Tissue Repair Regular anatomy: Pgs 100-101
Honors Anatomy: Pgs Be prepared to discuss this section and answer questions from me. Tortora & Grabowski 9/e 2000 JWS
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Read pages 140-141 Inflammation and Regeneration
Bellringer Read pages Inflammation and Regeneration Describe the process of healing an injured tissue This should take you more than 5 minutes to complete!! Tortora & Grabowski 9/e 2000 JWS
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