1. Microscopic Structure of the Male Genital Organs
Dr. Sama-ul-Haque
Dr Rania Gabr

2. Objectives Describe the microscopic structure of the testis.
Describe the microscopic structure of the epididymis and ductus deferens.
Discuss the microscopic structure of the seminal vesicle and prostate gland.
Discuss the microscopic structure of the penis.

3. INTRODUCTION Male gonad Testis A paired duct system
Ductuli efferentes, epididymis, ductus deferens and ejaculatory duct
Exocrine glands
Seminal vesicles and prostate gland
Penis

4. Testis Tunica Albuginea: Connective tissue capsule Tunica Vasculosa:
Vascular layer of loose connective tissue
Interstitial connective tissue:
Connective tissue extends inward from the tunica Vasculosa

5. Testis Seminiferous tubules:
Stratified epithelium (germinal epithelium) contains two types of cells
1.Spermatogenic cells: Produce Sperms
2.Sertoli cells (Sustentacular cells): For nourishment

6. Testis
Fibrous Septa:
Extending from mediastinum testis towards the tunica albuginea
Interstitial cells (of Leydig):
Epithelial cells, secrete testosterone (male sex hormone)

7. Straight tubules, Rete testis & Ductuli efferentes
Cuboidal or low columnar epithelium
Rete Testis:
Simple squamous to low cuboidal or low columnar epithelium
Ductuli efferentes (Efferent ductules):
Epithelium contains two groups of cells:
1. Tall columnar cells with cilia
2. Cuboidal cells with microvilli

8. Seminiferous tubules, Straight tubules, Rete testis & Ductuli efferentes

9. Spermatogenesis in Seminiferous tubules

10. SPERMATOGENIC CELLS
(1) Spermatogonia:
(2) 1ry Spermatocytes.
(3) 2ry Spermatocytes.
(4) Spermatids.
(5) Spermatozoa.

11. Stages of Spermatogenesis
Spermatogonia (Immature Spermatogenic cells)
Divide into three types:
1.Pale Type A Spermatogonia
2.DarkType A Spermatogonia
3.Type B Spermatogonia
Type B Spermatogonia produces Primary Spermatocytes

12. Stages of Spermatogenesis
Type B Spermatogonia produces Primary Spermatocytes
Primary Spermatocytes produces Secondary Spermatocytes (1st Meiotic Division)
SecondarySpermatocytes produces Spermatids (2nd Meiotic Division)
Spermatids differentiate into Sperms by the process of Spermiogeneis

13. Stages of Spermatogenesis

14. Seminiferous tubules

15. Ductuli efferentes & Tubules of the Ductus Epididymis

16. Tubules of the Ductus Epididymis
Pseudostratified Columnar Epithelium
Principal cells: Tall Columnar epithelium with Stereocilia (Long branching Microvilli)
Basal Cells
Thin Layer of Smooth Muscle surrounds each tubule
Tubules surrounded by Connective tissue

17. Tubules of the Ductus Epididymis

18. Ductus (Vas) Deferens Irregular lumen with longitudinal mucosal Folds
Lumen is lined by Pseudostratified Columnar Epithelium with Stereocilia
Thin Mucosa
Thick Muscularis (Three Smooth Muscle Layers)
1. Inner Longitudinal
2. Middle Circular
3. Outer Longitudinal
Adventitia

19. Ductus (Vas Deferens)

20. Ampulla of Vas Deferens
Lumen is larger then vas deferens
Numerous irregular, branching mucosal folds
Deep Glandular Crypts
Simple Columnar Epithelium

21. Prostate Gland Prostatic urethra lined by Transitional epithelium
Small, branched tubuloacinar prostatic glands
Prostatic Concretions (Corpora Amylacea) Solid Secretory Aggregations in the Acini
Fibromuscular Septa with Smooth muscle bundles
Colliculus Seminalis: Smooth dome-shaped structure of dense fibromuscular stroma (Gives crescent shape to prostatic urethra)

22. Prostate Gland
Prostatic sinuses (Excretory ducts of prostatic glands open here)
Prostatic utricle is a sac in the middle of colliculus seminalis
Ejaculatory ducts open at colliculus seminalis

23. Prostate Gland & Prostatic Urethra

24. Prostate Gland (Glandular Acini & Prostatic Concretions)

25. Seminal Vesicle Convoluted and Irregular Lumina
Primary mucosal folds branch into Secondary mucosal folds
Secondary mucosal folds anastomose and form irregular cavities called Mucosal Crypts

26. Seminal Vesicle Lamina Propria projects into these folds
Glandular epithelium is low columnar or cuboidal
Two layers of smooth muscle
1. Inner circular layer
2.Outer longitudinal layer
Adventitia

27. Seminal Vesicle

28. Penis Two Dorsal Corpus Cavernosa
Single Ventral Corpus Spongiosum carrying urethra in its whole length
Trabeculae with collagenous, elastic & smooth muscle fibers surround & form cavernous sinuses (veins)
Tunica Albuginea (Thick Connective tissue capsule)
surrounds Corpus Cavernosa & forms Median
Septum

29. Penis
Tunica Albuginea (Thin layer of connective tissue with smooth muscle fibers & elastic fibers)
surrounds Corpus Spongiosum
Deep Penile (Buck’s) Fascia (Loose connective tissue surrounding all)
Dermis (Contains Smooth muscle “dartos”)
Epidermis (Stratified squamous keratinized Epithelium)

30. Penis

31. Thank you