Presentation is loading. Please wait.

Presentation is loading. Please wait.

Figure 3. Elevation of p53 and its acetylation after treatment with FK866 and nicotinamide adenine dinucleotide (NAD+). Cells were treated for 72 hours.

Published byAdam Alban McDaniel Modified over 6 years ago

Similar presentations

Presentation on theme: "Figure 3. Elevation of p53 and its acetylation after treatment with FK866 and nicotinamide adenine dinucleotide (NAD+). Cells were treated for 72 hours."— Presentation transcript:

1 Figure 3. Elevation of p53 and its acetylation after treatment with FK866 and nicotinamide adenine dinucleotide (NAD+). Cells were treated for 72 hours with FK866 (10 nM) or FK866+NAD+ (10 µM). (A) p53 protein levels in treated and control cells; (B) acetylated-p53 levels in treated and control cells; and (C) Western blotting evaluation of the effects of FK866 on p53 and its acetylated form. This experiment was repeated three times. Data from one representative experiment is shown. *p<0.05 compared to control. Figure 3. Elevation of p53 and its acetylation after treatment with FK866 and nicotinamide adenine dinucleotide (NAD+). Cells were treated for 72 hours with FK866 (10 nM) or FK866+NAD+ (10 µM). (A) p53 protein levels in treated and control cells; (B) acetylated-p53 levels in treated and control cells; and (C) Western blotting evaluation of the effects of FK866… J Breast Cancer Mar;20(1):

Download ppt "Figure 3. Elevation of p53 and its acetylation after treatment with FK866 and nicotinamide adenine dinucleotide (NAD+). Cells were treated for 72 hours."

Similar presentations

Supplementary Figure 1. Caspase 8 expression and activation and Fas expression in NSCLC and normal lung cell lines. A Western blot analysis of DR4 and.

Supplementary Figure 1. Caspase 8 expression and activation and Fas expression in NSCLC and normal lung cell lines. A Western blot analysis of DR4 and.
Supplementary Figure 1: Co-treatment with SAHA and PLX4720 increases the level of a ~50kD fragment of PARP. Whole cell lysates from MM200 and Sk-Mel-28.

Supplementary Figure 1: Co-treatment with SAHA and PLX4720 increases the level of a ~50kD fragment of PARP. Whole cell lysates from MM200 and Sk-Mel-28.
H1299 Vector H1648 TUSC2 TUSC2 -ER 2.3 uM ER H1299 Vector TUSC2 TUSC2 -ER 2.3 uM ER H1299 Vector H1648 TUSC2 TUSC2 -ER 2.3 uM ER H1299 Vector TUSC2 TUSC2.

H1299 Vector H1648 TUSC2 TUSC2 -ER 2.3 uM ER H1299 Vector TUSC2 TUSC2 -ER 2.3 uM ER H1299 Vector H1648 TUSC2 TUSC2 -ER 2.3 uM ER H1299 Vector TUSC2 TUSC2.
ER  HSP90 DMSO 200  M I3C30  M DIM200  M TRYPTOPHOL Supplemental Figure 1. DIM and Tryptophol fail to induce the downregulation of ER  seen with I3C.

ER  HSP90 DMSO 200  M I3C30  M DIM200  M TRYPTOPHOL Supplemental Figure 1. DIM and Tryptophol fail to induce the downregulation of ER  seen with I3C.
Figure 7.1 Energy for Life. Figure 7.2 Oxidation and Reduction Are Coupled.

Figure 7.1 Energy for Life. Figure 7.2 Oxidation and Reduction Are Coupled.
CELLULAR RESPIRATION Part II. In the presence of O 2 we move through the Krebs cycle and the electron transport chain to produce 32-36 ATP molecules total.

CELLULAR RESPIRATION Part II. In the presence of O 2 we move through the Krebs cycle and the electron transport chain to produce ATP molecules total.
Nicotinamide Phosphoribosyltransferase: A Potent Therapeutic Target in Non-small Cell Lung Cancer with Epidermal Growth Factor Receptor-Gene Mutation 

Nicotinamide Phosphoribosyltransferase: A Potent Therapeutic Target in Non-small Cell Lung Cancer with Epidermal Growth Factor Receptor-Gene Mutation 
Figure 3. Synergistic effects of the combination of trabectedin and olaparib on poly(ADP-ribosyl)ation and DNA damage in four different breast cancer cell.

Figure 3. Synergistic effects of the combination of trabectedin and olaparib on poly(ADP-ribosyl)ation and DNA damage in four different breast cancer cell.
B A P-AXL P-AXL AXL AXL P-MET P-MET MET MET P-Akt-473 P-Akt-473 AKT

B A P-AXL P-AXL AXL AXL P-MET P-MET MET MET P-Akt-473 P-Akt-473 AKT
Figure 5. FK866 caused apoptosis in MCF-7 cells while nicotinamide adenine dinucleotide (NAD+) reversed FK866-induced apoptosis. (A) Representative quadrant.

Figure 5. FK866 caused apoptosis in MCF-7 cells while nicotinamide adenine dinucleotide (NAD+) reversed FK866-induced apoptosis. (A) Representative quadrant.
Figure 1. WA down-regulates H

Figure 1. WA down-regulates H
From: Regulation of ADAM10 and ADAM17 by Sorafenib Inhibits Epithelial-to-Mesenchymal Transition in Epstein-Barr Virus–Infected Retinal Pigment Epithelial.

From: Regulation of ADAM10 and ADAM17 by Sorafenib Inhibits Epithelial-to-Mesenchymal Transition in Epstein-Barr Virus–Infected Retinal Pigment Epithelial.
Fig. 5. The measurement of phosphorylation of p53 level in N2A cells under high glucose condition and agmatine treatment. (A, B) p53 phosphorylation levels.

Fig. 5. The measurement of phosphorylation of p53 level in N2A cells under high glucose condition and agmatine treatment. (A, B) p53 phosphorylation levels.
Figure 2. Histopathologic findings

Figure 2. Histopathologic findings
From: An Investigative Peptide–Acyclovir Combination to Control Herpes Simplex Virus Type 1 Ocular Infection Invest. Ophthalmol. Vis. Sci.. 2013;54(9):6373-6381.

From: An Investigative Peptide–Acyclovir Combination to Control Herpes Simplex Virus Type 1 Ocular Infection Invest. Ophthalmol. Vis. Sci ;54(9):
p < 0.001 Figure S1 p55 viral protein level Relative HIV-1

p < Figure S1 p55 viral protein level Relative HIV-1
Dioufa et al. Supplemental Materials.

Dioufa et al. Supplemental Materials.
سرطان الثدي Breast Cancer

سرطان الثدي Breast Cancer
A 4 Band intensity (relative unit) 3 2 1 MMP-9 MMP-2 B C 4 4

A 4 Band intensity (relative unit) MMP-9 MMP-2 B C 4 4
MEL23 and MEL24 inhibit Mdm2 and p53 ubiquitination in cells.

MEL23 and MEL24 inhibit Mdm2 and p53 ubiquitination in cells.

Similar presentations

Ads by Google