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CARIS annual review What’s new ?
Ty Dewi Sant Cardiff University 6th November 2013
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Research involving CARIS
Research Programme Research involving CARIS Pharmacovigilance Drugs taken in the first trimester Antiepileptics – ongoing since 2008 EuroMedicat – Insulin Antiasthmatics SSRIs Thyroxine
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Patau syndrome (T13) rates by maternal age
3 year rolling rates per 10,000 total births. CARIS data 1998 to 2011
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Further questions Is this decline real or just related to reporting?
Research Programme Further questions Is this decline real or just related to reporting? Is it significant? What has changed over the years (assisted conception, folic acid, paternal age)? Does it occur in other anomalies?
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Down syndrome (T21) rates by maternal age
Rates per 10,000 total births. CARIS data 1998 to 2011
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Edwards syndrome (T18) rates by maternal age
3 year rolling rates per 10,000 total births. CARIS data 1998 to 2011
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Baby hearts project Risk factors for congenital heart disease
University of Ulster Swansea & Cardiff Universities CARIS
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Preconceptual Counselling
Reasons why high congenital anomaly rates in Wales obesity epidemic smoking, alcohol, drugs medical disorders maternal deaths due to chronic conditions Barriers why not unplanned pregnancy not trying/not preventing lack of public awareness
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Survey of 100 pregnant women
Pre–conceptual counselling? Text, tables and graphs as appropriate. Visible colours. 12
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Would they have liked to receive PCC?
Results Would they have liked to receive PCC? N = 74 Text, tables and graphs as appropriate. Visible colours. 13
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Thank you for your help and contributions to
Thank you for your help and contributions to CARIS over the past 15 years
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