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BREAST CANCER A full classification includes histopathological type, grade, stage (TNM), receptor status, and the presence or absence of genes as determined.

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Presentation on theme: "BREAST CANCER A full classification includes histopathological type, grade, stage (TNM), receptor status, and the presence or absence of genes as determined."— Presentation transcript:

1 BREAST CANCER A full classification includes histopathological type, grade, stage (TNM), receptor status, and the presence or absence of genes as determined by DNA testing: Histopathology. breast cancer has several different histologies, Carcinoma in situ Invasive Carcinoma (i.e. lobular, ductal NOS, mucinous) Grade. Grading focuses on the appearance of the breast cancer cells compared to the appearance of normal breast  (nuclear, architecture, mitotic) Stage. The TNM classification for staging breast cancer is based on the size of the cancer where it originally started in the body and the locations to which it has travelled.  Receptor status. Cells have receptors on their surface and in their cytoplasm and nucleus. (ER, PR, Her-2) DNA-based classification. Understanding the specific details of a particular breast cancer may include looking at the cancer cell DNA or RNA by several different laboratory approaches.

2 Well Differentiated Poorly Differentiated

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