1. Journal of Microbiology, Immunology and Infection
Prevalence and comparative analysis of the type IV secretion system in Aggregatibacter actinomycetemcomitan 
Chih-Chin Liu, Chang-Hua Chen, Chuan Yi Tang, Kuan-Hsueh Chen, Zhao-Feng Chen, Shih-Hao Chang, Chi-Ying Tsai, Ming-Li Liou 
Journal of Microbiology, Immunology and Infection 
DOI: /j.jmii
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2. Figure 1
Phylogenetic analysis of 20 A. actinomycetemcomitans genomes. The phylogenetic tree was constructed using CVTree, and the neighbour-joining tree was constructed using MEGA6. The genome of Agrobacterium tumefaciens str. C58 was used as the outgroup to root the tree.
Journal of Microbiology, Immunology and Infection DOI: ( /j.jmii )
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3. Figure 2
Phylogenetic analysis of four P-type T4SS protein sequences from A. actinomycetemcomitans genomes and/or plasmids. (A) MagB04, (B) MagB08, (C) MagB10, and (D) MagB12. T4SS proteins belonging to T4SSAaI and T4SSAaII are boxed in blue and red, respectively. The homologous VirB/VirD family proteins from the pTi plasmid were used as outgroups to root the trees. LAP, localised aggressive periodontitis; GAP, generalised aggressive periodontitis; CP, chronic periodontitis; G, chronic gingivitis; H, periodontally healthy.
Journal of Microbiology, Immunology and Infection DOI: ( /j.jmii )
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4. Figure 3
The T4SS transfer system. (A) A topological presentation of the P-like T4SS transfer apparatus from the A. actinomycetemcomitans plasmids pVT745 and S25, based on Waksman and Orlova.38 (B) Comparison between the P-type T4SS T4SSAaI (in plasmids pVT745, S23A, and S57) and T4SSAaII (in plasmid S25). Genes with the same colour represent homologous gene products, while gene products with no homology to other T4SS subfamilies are shown in white. The gene sizes are relative to each other.
Journal of Microbiology, Immunology and Infection DOI: ( /j.jmii )
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5. Figure 4
Prevalence of A. actinomycetemcomitans serotypes and their association with T4SSs in a Taiwanese population. (A) 100 subjects, including 20 periodontitis patients (B) and 80 normal subjects (C). (D) Prevalence of T4SSs and their location in plasmids in 100 subjects.
Journal of Microbiology, Immunology and Infection DOI: ( /j.jmii )
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