1. Key Area 6: Metabolic Pathways
KA 6: Metabolic Pathways
(E) Control of metabolic pathways through inhibitors
(A) Metabolism
(B)
Control of metabolic pathways through enzymes
(C) Induced fit and Active sites
(D)
Effect of substrate and end-product concentrations

2. Metabolic Pathways (a)
Revise your knowledge on the properties of enzymes
State what is meant by metabolism and metabolic pathway
State what is meant by an anabolic pathway (and make reference to energy)
State what is meant by a biosynthetic reaction
State what is meant by an catabolic pathway (and make reference to energy)
Give an example of an anabolic and catabolic reaction

3. What do all these words mean?
Key Words
Anabolism
Induced Fit
Catabolism
Degradation
Biosynthetic
Synthesis
Enzyme
Amylase
Metabolism
Catalase
Substrate
Active site
Activation energy
Specificity
TASK:
Think / Pair / Share
What do all these words mean?

4. What Can You Remember about…
ENZYMES
Multi Choice Quiz!

5. Q1. Enzymes… a) speed up reactions and remain unchanged
d) slow down reactions and are used up in the reaction
c) speed up reactions and are used up in the reaction
b) slow down reactions and remain unchanged

6. Q2. Enzymes are made of… a) protein d) minerals c) fats
b) carbohydrate

7. Q3. What is an active site?
a) The place on a substrate where the enzyme binds.
d) The place on an enzyme where the substrate binds.
c) The place on the product where the substrate binds.
b) The place on the substrate where the product binds.

8. Q4. Which term best describes a denatured enzyme?
a) Its active site has changed shape.
d) Attached to the substrate.
c) Working at its fastest rate.
b) Dead.

9. Q5. What will bind to an active site?
a) All types of substrate molecule.
d) One type of product molecule.
c) One type of substrate molecule.
b) All types of product molecule.

10. Q6. Enzymes will work at … a) only one pH d) acidic pHs
c) a range of pHs
b) all pHs

11. Q7. Which graph shows the effect of temperature on enzyme activity?d) c) b) a) a)
activity
activity
temperature
temperature
activity
activity
temperature
temperature

12. Q8. Which of the following is correct?
a) The substrate of phosphorylase is hydrogen peroxide.
d) The substrate of phosphorylase is starch.
c) The substrate of phosphorylase is protein.
b) The substrate of phosphorylase is glucose-1-phosphate.

13. Q9. Which of the following is correct?
a) Starch catalase maltose
d) Starch catalase glucose
c) Starch amylase glucose
b) Starch amylase maltose

14. Q10. Which of the following is correct?
Amylase is a synthesis enzyme.
Catalase is a breakdown enzyme.
d) Amylase is a synthesis enzyme.
Phosphorylase is a breakdown enzyme.
c) Catalase is a synthesis enzyme.
Amylase is a breakdown enzyme.
b) Phosphorylase is a synthesis enzyme.

15. Q1. Enzymes… a) Speed up reactions and remain unchanged
b) slow down reactions and remain unchanged
c) speed up reactions and are used up in the reaction
d) slow down reactions and are used up in the reaction

16. Q2. Enzymes are made of… a) Protein b) carbohydrate c) fats
d) minerals

17. Q3. What is an active site?
a) The place on a substrate where the enzyme binds.
b) The place on the substrate where the product binds.
c) The place on the product where the substrate binds.
d) The place on an enzyme where the substrate binds

18. Q4. Which term best describes a denatured enzyme?
a) The active site has changed shape
b) Dead.
c) Working at its fastest rate.
d) Attached to the substrate.

19. Q5. What will bind to an active site?
a) All types of substrate molecule.
b) All types of product molecule.
c) One type of substrate molecule
d) One type of product molecule.

20. Q6. Enzymes will work at … a) only one pH b) all pHs c) A range of pHs
d) acidic pHs

21. Q7. Which graph shows the effect of temperature on enzyme activity?b) a)
activity
activity
temperature
temperature c) d)
activity
activity
temperature
temperature

22. Q8. Which of the following is correct?
a) The substrate of phosphorylase is hydrogen peroxide.
b) The substrate of phosphorylase is glucose-1-phosphate
c) The substrate of phosphorylase is protein.
d) The substrate of phosphorylase is starch.

23. Q9. Which of the following is correct?
a) Starch catalase maltose
b) Starch amylase Maltose
c) Starch amylase glucose
d) Starch catalase glucose

24. Q10. Which of the following is correct?
Amylase is a synthesis enzyme.
Catalase is a breakdown enzyme.
b) Phosphorylase is a synthesis enzyme.
Catalase is a breakdown enzyme.
c) Catalase is a synthesis enzyme.
Amylase is a breakdown enzyme.
d) Amylase is a synthesis enzyme.
Phosphorylase is a breakdown enzyme.