1. Johns Hopkins Hospital Malignant and Benign Brain/CNS
February 1, 2009

2. Brain/CNS (Benign/Malignant Combined) Analytic vs
Brain/CNS (Benign/Malignant Combined) Analytic vs. Non-Analytic n = 2153
* Analytic - Initially Diagnosed and/or received all or part of 1st course treatment at JHH
**Non-Analytic - Initially diagnosed & treated elsewhere to JHH for treatment of recurrent, metastatic or progression of disease.

3. Brain/CNS (Benign/Malignant Combined) Age at Diagnosis by Gender, All Cases 2003-2007 n = 2153
298
243
227
194
183
163
121
129 96 78 74 70 66 58 67 19 40 27

4. Brain/CNS (Benign/Malignant Combined) by Race, All Cases 2003-2007 n = 2153
939
865 52 46
120 19 28 84

5. Brain/CNS Benign vs. Malignant, All Cases 2003-2007 n = 2153

6. Brain/CNS (Benign/Malignant Combined) by Maryland Counties 2003-2007 n = 1124

7. Brain/CNS (Benign/Malignant Combined) by State at Diagnosis 2003-2007 n = 2153

8. Johns Hopkins Hospital Malignant Brain/CNS

9. Brain/CNS Malignant Analytic vs. Non-Analytic 2003-2007 n = 989
* Analytic - Initially Diagnosed and/or received all or part of 1st course treatment at JHH
**Non-Analytic - Initially diagnosed & treated elsewhere to JHH for treatment of recurrent, metastatic or progression of disease.

10. Brain vs CNS Malignant by Year 2003-2007 n = 989
* Analytic - Initially Diagnosed and/or received all or part of 1st course treatment at JHH
**Non-Analytic - Initially diagnosed & treated elsewhere to JHH for treatment of recurrent, metastatic or progression of disease.

11. Brain/CNS Malignant Age at Diagnosis by Gender, All Cases 2003-2007 n = 989
124 91 87 94 69 66 61 60 56 43 51 42 39 29 29 26 14 8

12. Brain/CNS Malignant Race by Gender, All Cases 2003-2007 n = 989
483
354 49 37 14 28 12 12

13. Brain/CNS Malignant by State at Diagnosis 2003-2007 n = 989

14. Brain/CNS Malignant by Maryland Counties 2003-2007 n = 549

15. Brain Malignant* by Treatment, Class 1-2** 2003-2007 n = 728
*Excludes CNS Tumors
**class 1 – Diagnosed at JHH and part/all of first course treatment at JHH
class 2 – Diagnosed elsewhere and all/part of first course treatment at JHH

16. CNS Malignant by Treatment, Class 1-2** 2003-2007 n = 91
Died before tx – 11
Refused – 10
Unknown – 6
Xrt recomm unk if done – 3
Contraindicated - 1
**class 1 – Diagnosed at JHH and part/all of first course treatment at JHH
class 2 – Diagnosed elsewhere and all/part of first course treatment at JHH

17. Brain Malignant* by Histology 2003-2007 n = 879
*Excludes CNS Tumors

18. CNS Malignant* by Histology 2003-2007 n = 110
*Excludes CNS Tumors

19. Brain Malignant JHH vs. NCDB Observed Survival Rates 1998-2002
The SEER 9 registries are Atlanta, Connecticut, Detroit, Hawaii, Iowa, New Mexico, San Francisco-Oakland, Seattle-Puget Sound, and Utah. Data are available for cases diagnosed from 1973 and later for these registries with the exception of Seattle-Puget Sound and Atlanta. The Seattle-Puget Sound and Atlanta registries joined the SEER program in 1974 and 1975, respectively.

20. CNS Malignant JHH vs. NCDB Observed Survival Rates 1998-2002
The SEER 9 registries are Atlanta, Connecticut, Detroit, Hawaii, Iowa, New Mexico, San Francisco-Oakland, Seattle-Puget Sound, and Utah. Data are available for cases diagnosed from 1973 and later for these registries with the exception of Seattle-Puget Sound and Atlanta. The Seattle-Puget Sound and Atlanta registries joined the SEER program in 1974 and 1975, respectively.

21. Johns Hopkins Hospital Benign Brain/CNS Tumors

22. Brain/CNS Benign Analytic vs. Non-Analytic 2003-2007 n = 1164

23. Brain/CNS Benign Brain vs. CNS 2003-2007 n = 1164

24. Brain/CNS Benign Age at Diagnosis by Gender, All Cases 2003-2007 n = 1164
207
167
119
114
100 87 76 67 55 14 31 37 35 7 6 5 18 19

25. Brain Benign* Age at Diagnosis by Gender, All Cases 2003-2007 n = 9111 11 9 8 8 6 6 5 5 5 4 4 4 3 1 1
*Excludes CNS Tumors

26. CNS Benign Age at Diagnosis by Gender, All Cases 2003-2007 n = 1073
199
163
113
113 95 71 78 64 47 35 3 1 8 20 26 14 5 18

27. Brain/CNS Benign Race by Gender, All Cases 2003-2007 n = 1164
585
382 34 35 5 16 24 83

28. Brain Benign* Race by Gender, All Cases 2003-2007 n = 9142 39 4 5 1
*Excludes CNS Tumors

29. CNS Benign Race by Gender, All Cases 2003-2007 n = 1073
543
343 78 31 16 24 33 5

30. Brain/CNS Benign by State at Diagnosis 2003-2007 n=1164

31. Brain/CNS Benign by Maryland Counties 2003-2007 n= 575

32. Brain/CNS Benign by Treatment, Class 1-2* 2003-2007 n= 1005
*class 1 – Diagnosed at JHH and part/all of first course treatment at JHH
class 2 – Diagnosed elsewhere and all/part of first course treatment at JHH

33. Brain Benign* by Histology, All Cases 2003-2007 n = 91
*Excludes CNS Tumors

34. CNS Benign by Histology, All Cases 2003-2007 n = 1073