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Introduction to Parasitology
Jafari R Isfahan University of Medical Sciences
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Human disease agents a-Viruses b-Prokaryotes c-Eukaryotes
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Symbiosis Types of life
Merriam-Webster dictionary “The relationship between two different kinds of living things that live together and depend on each other”
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Symbiosis Commensalism Mutualism Phoresis Parasitism
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Commensalism “A relationship where one species obtains food or shelter from the other species. Does not harm or help the other species”
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Mutualism “relationship where both species benefit from the relationship”
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Phoresis “The phoront, is mechanically transported by its host. Neither organism is physiologically dependent on the other”
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Parasitism “A relationship between two species in which one species (the parasite) nourishes itself to the disadvantage of the other species (the host)”
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Terminology Parasite: an organism which lives in or on another organism (its host) and benefits by deriving nutrients at the other's expense. Host: an animal or plant on or in which a parasite or commensal organism lives Parasitology: study of parasites, their hosts, and the relationship between them Vector: an organism, typically a biting insect or tick, that transmits a disease or parasite from one animal or plant to another.
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Types of parasites Ectoparasite: e.g. fleas, Ticks
Endoparasite Facultative-p Obligate-p Permanent-p Temporary-p Accidental-p Abberant-p Types of parasites Ectoparasite: e.g. fleas, Ticks Endoparasite: e.g. malaria Facultative parasite: e.g. free living Amebae Obligate parasite: e.g. filaria Permanent parasite: e.g. intestinal worms Temporary parasite: e.g. mosquitoes Accidental parasite: e.g. Dicrocoelium Abarent parasite: e.g. Toxocara
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Types of hosts Definitive host: e.g. Anopheles for malaria
Intermediate host: e.g. human for malaria Reservoir host: e.g. Beaver for Giardia Paratenic host: e.g. 2nd Fish for Diphyllobothrium
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Vector - Mechanical Vector - Biological Vector
A vector that conveys pathogens to a susceptible individual without essential biologic development. E.g. the transfer of septic organisms on the feet or mouth parts of the housefly - Biological Vector A vector that conveys pathogens to a susceptible individual with essential biologic development E.g. the transfer of the deadly disease malaria by mosquitoes
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Life cycle Zoonotic A disease that can be passed between animals and humans Anthroponotic An infection in which a disease causing agent carried by humans is transferred to other human or even animals
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Terminology Infestation Infection: Disease Super infection
Re infection Retro infection Auto infection Disease
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Source of infection or infestation
Soil born Water born Food born Vector born Fomite Zoonosis
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Portal of entry Mouth : - Water Skin : - from the soil
- Food Skin : - from the soil - from the water - by blood-sucking arthropods Inhalation: of air-born eggs or cyst Transplacental ( congenital ) Transmammary ( milk ) infection Sexually transmitted infection
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Systematic classification of living things
Animalia Kingdomسلسله => Metazoa, Protozoa Phylumشاخه Classرده Orderراسته Familyخانواده Genusجنس Speciesگونه Strain سویه
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Kingdom - Metazoa - Protozoa
Using light microscope; (Amebae, Flagellates, Ciliates, Sporozoea) Using electronic microscopic; (Sarcomastigophora, Apicomplexa, Microspora) - Metazoa Helminthes; Nematoda, PlatyHelminthes (Trematoda,Cestoda) Acanthocephala
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Protozoa Protoplasm Cytoplasm Ectoplasm Endoplasm Nucleoplasm
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Ectoplasm Function Endoplasm Function
1-Protection of the organism Locomotor aparatus 3-Food ingestion Respiration 5-Discharge of metabolic wastes Endoplasm Function Containing ; mitochondria, golgi, Glycogen vacuoles & chromatidal bodies, Food vacuoles, ... Food synthesis Excretory vacuoles (collection of fluid wastes) Contractive vacuoles (maintain osmotic pressure)
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Vital function -Locomotion: locomotory organelles;
1 Pseudopodia Cilia Flagellum 4 Undulating membran without locomotory organell (gliding movement) -Respiration: 1- aerobic (blood & tissue protozoa) 2- micro-aerophilic (intestinal protozoa) -Nutrition: liquid absorption cell mouth (cytostom) pinocytosis phagocytosis
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Reproduction of protozoa
Asexual 1- Binary-fission : (Amaebae) 2- Endodiogeny : Coccidia 3- Schizogony (merogony): Plasmodium Sexual 1- Syngamy: Free-flagellates 2- Sprogony : Malaria parasites 3-Conjugation: Ciliata
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Life cycle of protozoa Trophozoite transmission: (e.g.; Enta. Gingivalis) Cyst transmission: Entamoeba
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Thanks
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