1. Protein Synthesis: Transcription, Translation, and Mutations

2. Think-Pair-Share: What can you identify/ remember about this topic?

3. What are we looking at?
A cell

4. Where is all the genetic information stored for a cell?
The nucleus

5. It sends the message through mRNA
How does this DNA get the message out of the nucleus to other parts of the cell?
It sends the message through mRNA

6. Where does mRNA take this message to be turned into a protein?
Into the cytoplasm, to a ribosome (grey circle around the mRNA)

7. Which comes first alphabetically, translation or transcription?
then
TransLation
Transcription happens first, in the nucleus, then TransLation occurs at the ribosome to make a protein

8. You will use this page to do your practice problems

9. DNA RNA A U T A C G G C Always look up your mRNA to find the
amino acid.
TAG
CGA
AUC
GCU
UAG
CGA
Iso.
Ala.

10. Codon Bingo DNA RNA A U T A C G G C DNA mRNA tRNA A.A
Always look up your mRNA to find the
amino acid.
1st round: Call out DNA
2nd round: Call out mRNA
3rd round: Call out tRNA

11. Identify this Process
On the back of your bingo card, write whether the process you see is Transcription, Translation, or all of Protein Synthesis.
When I say so, show me your board.
Have a reason for why you picked your answer. (ex: It had DNA, It had RNA, it occurred in the nucleus, It occurred outside the nuceleus, I saw tRNA, etc)

18. leu
arg
ser
arg
U G C G U A G U C G G
cys
val
A wrong protein, or a non-functioning protein
can be made.
Val
Block this out

19. ADDED NO STOP CODON DIFFERENT NUCLEOTIDE CAN CANNOT REMOVED
Swapped out NO
DIFFERENT
STOP
CODON
DIFFERENT

20. Mutations Card Sort
Each group of students get a set of cards and each student gets a student handout and a codon chart.
Students must sort the cards in to groups. Each group must have: 1) an image or mutation example card, 2) one or more mutation type cards, and 3) a description card .
Note: There will be more than one type of mutation card in each group except non-disjunction.
Students should use their student handout to label each example and take any needed notes.

21. Check Your Answers!