1. Chromosomal Basis for Inheritance
General Biology
SUNY Orange at S. S. Seward Institute

2. 0.5 mm
Parent
Bud
(a) Hydra

4. Chromosomes in Motion
video

8. 22 + XX
22 + X
(b) The X-0 system

9. 76 + ZW
76 + ZZ
(c) The Z-W system

10. (d) The haplo-diploid system32
(Diploid) 16
(Haploid)
(d) The haplo-diploid system

12. 0.5 mm
Parent
Bud

14. Test cross -

18. QV = 38 extra credit: Where’s U?
Chromosomal Mapping
The following genes have been determined to have recombination rates as follows:
QS = 24
RV = 2
SR = 12
QR = Draw the gene map.
TS = 4
QT = 20
QV = extra credit: Where’s U?

20. Epigenetics
is the study of heritable changes in gene expression or cellular phenotype caused by mechanisms other than changes in the underlying DNA sequence
refers to functionally relevant modifications to the genome that do not involve a change in the nucleotide sequence
PBS video

22. Calico Cat Genetics

25. Aneuploidy Aneuploidy – an abnormal number of chromosomes
Usually the result of non-disjunction
Can be extra or missing chromosomes

30. Sex Linked Aneuploidy XXY – Kleinfelter Syndrome XO – Turner Syndrome
XYY -
XXX -

31. Genomic Imprinting
For some traits, expression will depend on whether the allele is inherited from the male or female parent
Identified in 2-3 dozen traits in mammals
Often genes controlling development
Mechanism is probably DNA methylation

35. Epigenetics
epigenetics is the study of heritable changes in gene expression or cellular phenotype caused by mechanisms other than changes in the underlying DNA sequence

36. Organelle Genes a.k.a – extranuclear genes
Chloroplasts and mitochondria have DNA and genes

37. Essay
What is epigenetics and why is it important?