1. Systemic Sclerosis
Criteria

2. Systemic sclerosis (SSc) criteria
Patients are said to have Systemic Sclerosis (SSc) by ACR criteria if they have:
the one major criterion, or
2 of the 3 minor criteria

3. Systemic sclerosis criteria
Major criterion:
Proximal scleroderma

4. Thick skin of fingers and hands (proximal scleroderma)

5. Thick skin of forearms (proximal scleroderma)

6. (proximal scleroderma)
Thick skin of torso
(proximal scleroderma)

7. Thick skin of face (proximal scleroderma)

8. Atrophic (thin) skin changes of face (proximal scleroderma)

9. Systemic sclerosis criteria
Major criterion:
Minor criteria:
Proximal scleroderma
Sclerodactyly

10. Sclerodactyly (early puffy fingers)

11. Taut, thick skin of fingers

12. Taut, thin skin of fingers

13. Systemic sclerosis criteria
Major criterion:
Minor criteria:
Proximal scleroderma
Sclerodactyly
Digital pitting scar

14. Digital tip pitting scars

15. Systemic sclerosis criteria
Major criterion:
Minor criteria:
(2 of the 3)
Proximal scleroderma
Sclerodactyly
Digital pitting scar
Interstitial change on chest x-ray

16. Interstitial change (x-ray)

17. Systemic sclerosis criteria (ACR)
Major criterion:
Minor criteria:
(2 of the 3)
Proximal scleroderma
Sclerodactyly
Digital pitting scar
Interstitial change on chest x-ray

18. Systemic sclerosis (SSc) criteria
Patients are said to have Systemic Sclerosis by ACR criteria if they have:
one major criterion or
2 of the 3 minor criteria
LeRoy & Medsger have suggested two additional criteria to diagnose mild SSc:
Raynaud’s phenomenon (plus both):
nailfold capillary abnormalities
SSc-specific antibodies (anti-centromere, anti-SCL-70, anti-PM-Scl, etc)

19. Raynaud’s phenomenon

20. Nailfold capillary abnormalities

21. Nailfold capillaroscopy
Supplies

22. Nailfold capillaroscopy
Technique

23. Nailfold capillary abnormalities
SSc
Normal
Adult DM
Childhood DM

24. SSc-specific antibodies
Readily available
Anti-centromere
Anti-SCL 70
Anti-PM/Scl
Not so available
Anti-Th/To
Anti-RNA
polymerase III
Anti-fibrillarin
Anti-centromere antibody

25. Systemic sclerosis (SSc) criteria
Patients are said to have Systemic Sclerosis by ACR criteria if they have:
one major criterion or
2 of the 3 minor criteria
LeRoy & Medsger have suggested two additional criteria to diagnose mild SSc:
Raynaud’s phenomenon (plus both):
nailfold capillary abnormalities
SSc-specific antibodies (anti-centromere, anti-SCL-70, anti-PM-Scl, etc)