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Published byJosé Francisco García Ayala Modified over 6 years ago
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Role of porins from Salmonella typhi in the induction of protective immunity.
Isibasi A, Paniagua J, Rojo MP, Martín N, Ramírez G, González CR, López- Macías C, Sánchez J, Kumate J, Ortiz-Navarrete V. Ann NY Acad Sci, 1994. Induction of antibodies against Salmonella typhi OmpC porin by naked DNA immunization. López-Macías C, López-Hernández MA, González CR, Isibasi A, Ortiz-Navarrete V. Ann NY Acad Sci, 1995.
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Induction of cellular immune response and anti-Salmonella enterica serovar typhi bactericidal antibodies in healthy volunteers by immunization with a vaccine candidate against typhoid fever. Immunol Lett, 2004. Salmonella porins induce a sustained, lifelong specific bactericidal antibody memory response. Immunology, 2006. The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response. Proc Natl Acad Sci USA, 2009.
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The capsular polysaccharide Vi from Salmonella typhi is a B1b antigen.
J Immunol 2012. Salmonella Typhi OmpS1 and OmpS2 porins are potent protective immunogens with adjuvant properties. Immunology, 2013. B1b cells recognize protective antigens after natural infection and vaccination. Front Immunol, 2014. Salmonella Typhi Porins OmpC and OmpF Are Potent Adjuvants for T- Dependent and T-Independent Antigens. Front Immunol, 2017.
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