1. Abnormal EEGs were found in 43–75% of autistic children and 82% of their EEGs; 46% had clinical seizures. Nearly all children with seizures had epileptiform activity, but almost 20% of those with spike discharges did not have clinical seizures. Slow-wave abnormalities were more frequent in the autistic individuals. Most epileptic discharges were localized spikes; some had multiple spike foci and, only on rare occasions, generalized spikes; 76.6% of the epileptic discharge foci were in the frontal region, 2.1% in the temporal region, 14.1% in the centro-parietal region, and 6.4% in the occipital region; 55.6% of the frontal spikes were at midline, approximately equal at Fz and Cz. The dipole of midline spikes was in the deep midline frontal region. These results suggest that frontal dysfunction is important in the mechanism and symptoms in autism.206,207
Source: Focal Epilepsy, Atlas of Pediatric EEG
Citation: Laoprasert P. Atlas of Pediatric EEG; 2011 Available at: Accessed: October 28, 2017
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