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Drugs
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- detect/ ID drugs in body fluid
- drug testing for potential employee, athlete, crime victims
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Toxicology Testing and Procedures
clues help determine which tests to do - ex. syringe, bottles TLC, GC, immunoassay - detect trace amounts of drugs in blood, urine, tissues once narrowed --> confirmed w/ GC-MS
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Reinsch Test heavy-metal poisoning
in HCl, metal ions produce silver colored coating on copper if +, then use emission spectroscopy or atomic absorption spectroscopy to ID/confirm
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Blood-Gas Screenings fire victims or cherry-red lividity
CO - use spectrophotometry or GC if no CO in fire victim --> died before fire; set to hide evidence
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Immunoassay relies on antigen-antibody response
antigen = substance that produces an immune response antibodies produced in immune cells to attach to specific antigens poisons/drugs = antigens
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detects amount of antibodies in blood or urine when specific drug antigens added to sample
antigens & antibodies bond Enzyme Multiplied Immunoassay Technique (EMIT) - detects certain drugs & their metabolites ex. cocaine, marijuana, heroin, amphetamines, barbituates, etc
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