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Effect of storage time on metabolite profile and alpha-glucosidase inhibitory activity of Cosmos caudatus leaves – GCMS based metabolomics approach  Neda.

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Presentation on theme: "Effect of storage time on metabolite profile and alpha-glucosidase inhibitory activity of Cosmos caudatus leaves – GCMS based metabolomics approach  Neda."— Presentation transcript:

1 Effect of storage time on metabolite profile and alpha-glucosidase inhibitory activity of Cosmos caudatus leaves – GCMS based metabolomics approach  Neda Javadi, Faridah Abas, Ahmed Mediani, Azizah Abd Hamid, Alfi Khatib, Sanimah Simoh, Khozirah Shaari  Journal of Food and Drug Analysis  Volume 23, Issue 3, Pages (September 2015) DOI: /j.jfda Copyright © Terms and Conditions

2 Fig. 1 Alpha glucosidase inhibitory activity and IC50 value of Cosmos caudatus samples at different storage times. Data are presented as mean ± SD, n = 7. Data in each column with different subscript letters are significantly different (p < 0.05). Journal of Food and Drug Analysis  , DOI: ( /j.jfda ) Copyright © Terms and Conditions

3 Fig. 2 Gas chromatography-mass spectrometry (GC-MS) total ion chromatogram of Cosmos caudatus (A) in fresh sample and (B) after 12 hours of storage. 1 = catechin; 2 = α-tocopherol; 3 = cyclohexen-1-carboxylic acid; 4 = benzoic acid; 5 = myo-inositol; 6 = stigmasterol; 7 = lycopene; 8 = sucrose; 9 = α-d-galactopyranose; 10 = turanose. Journal of Food and Drug Analysis  , DOI: ( /j.jfda ) Copyright © Terms and Conditions

4 Fig. 3 Orthogonal partial least squares (OPLS) score (A) and loading column plots (B) at different storage times (0 hours, 2 hours, 4 hours, 6 hours, 8 hours, 10 hours, and 12 hours) of Cosmos caudatus extracts. 1 = catechin; 2 = α-tocopherol; 3 = cyclohexen-1-carboxylic acid; 4 = benzoic acid; 5 = myo-inositol; 6 = stigmasterol; 7 = lycopene; 8 = sucrose; 9 = α-d-galactopyranose; 10 = turanose. Journal of Food and Drug Analysis  , DOI: ( /j.jfda ) Copyright © Terms and Conditions

5 Fig. 4 Prediction versus observation of IC50 values from all samples. The R² of the regression line indicates the goodness of fit between experimental observations and predicted model. R² in this correlation was Journal of Food and Drug Analysis  , DOI: ( /j.jfda ) Copyright © Terms and Conditions


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