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Published byKevin Warner Modified over 6 years ago
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Device for Shielding a Neurochemical Sampling Apparatus
Mark Reagan Anika Lohrentz David Leinweber Alison Boumeester Client: Ei Terasawa, Ph.D Advisor: Naomi Chesler, Ph.D
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Outline Background Design Objectives Previous Work New Designs
Design Matrix Ski Mask Bone Screws Reverse Cone Final Design
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Background Neurochemical collection from Rhesus macaques
Microdrive inserted into brain Confined to chairs 12 hour duration, every month Free movement preferable
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Design Objectives Protect microdrive Safe Lightweight Easy to use
Production Cost- $1000 Budget Forst SI, et al., Microdialysis methods for in vivo neropeptide measurement in the Stalk-median eminence in the Rhesus monkey, J Neurosci Methods (2007).
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Previous Work Spring 2008 Strap did not work Fall 2008 Too heavy
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Design Ideas Ski Mask Bone Screws Reverse Cone
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Ski Mask Pros Cons Minimal volume Aesthetically pleasing
Excessive wiggle room Complex set up Weight focused well above head
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Bone Screws Pros Cons Most stable attachment method
Invasiveness adds risk, administrative hurdles Juvenile skulls very thin Attachment points not absolute
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Reverse Cone Pros Cons Ample clearance around microdrive
Light weight, carried close to body Compatible with growing subjects Readily approvable and producible Cons Reaching into cone Monkey-proofing face hole
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Design Matrix Category Weight Bone Screws Ski Mask Reverse Cone Safety
40 30 25 35 Ease of Implementation 10 28 Practicality of Production 20 15 18 Comfort 5 7 8 Total 60 67 89
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Final Design Reverse Cone “Hospital” neck brace for support
Lining for “Head Cutout”: Suction Molding
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Questions?
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