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Volume 56, Issue 4, Pages (April 2012)

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Presentation on theme: "Volume 56, Issue 4, Pages (April 2012)"— Presentation transcript:

1 Volume 56, Issue 4, Pages 908-943 (April 2012)
EASL–EORTC Clinical Practice Guidelines: Management of hepatocellular carcinoma  European Association for the Study of the Liver, European Organisation for Research and Treatment of Cancer  Journal of Hepatology  Volume 56, Issue 4, Pages (April 2012) DOI: /j.jhep Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

2 Fig. 1 Incidence rates of primary liver cancer according to geographical distribution in Europe. Age-adjusted incidence rates per 100,000 of liver cancer in Europe in The color intensity is proportional to the magnitude of incidence. M, males; F, females. (Data from: Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. GLOBOCAN 2008, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10 [Internet]. Lyon, France: International Agency for Research on Cancer; Available from: Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

3 Fig. 2 Diagnostic algorithm and recall policy. ∗One imaging technique only recommended in centers of excellence with high-end radiological equipment. ∗∗HCC radiological hallmark: arterial hypervascularity and venous/late phase washout. Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

4 Fig. 3 Updated BCLC staging system and treatment strategy, 2011.
Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

5 Fig. 4 Representation of EASL–EORTC recommendations for treatment according to levels of evidence (NCI classification [2]) and strength of recommendation (GRADE system). RF, radiofrequency ablation; PEI, percutaneous ethanol injection; OLT, orthotopic liver transplantation; LDLT, living donor liver transplantation. Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

6 Fig. 5 Summary of trial design strategies and control groups. Adapted from Llovet et al. [164]. Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

7 Journal of Hepatology 2012 56, 908-943DOI: (10. 1016/j. jhep. 2011. 12
Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

8 Journal of Hepatology 2012 56, 908-943DOI: (10. 1016/j. jhep. 2011. 12
Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

9 Journal of Hepatology 2012 56, 908-943DOI: (10. 1016/j. jhep. 2011. 12
Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

10 Journal of Hepatology 2012 56, 908-943DOI: (10. 1016/j. jhep. 2011. 12
Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

11 Journal of Hepatology 2012 56, 908-943DOI: (10. 1016/j. jhep. 2011. 12
Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

12 Journal of Hepatology 2012 56, 908-943DOI: (10. 1016/j. jhep. 2011. 12
Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

13 Journal of Hepatology 2012 56, 908-943DOI: (10. 1016/j. jhep. 2011. 12
Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

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Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

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Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

16 Journal of Hepatology 2012 56, 908-943DOI: (10. 1016/j. jhep. 2011. 12
Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

17 Journal of Hepatology 2012 56, 908-943DOI: (10. 1016/j. jhep. 2011. 12
Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

18 Journal of Hepatology 2012 56, 908-943DOI: (10. 1016/j. jhep. 2011. 12
Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

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Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

20 Journal of Hepatology 2012 56, 908-943DOI: (10. 1016/j. jhep. 2011. 12
Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

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Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

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Copyright © 2012 European Association for the Study of the Liver Terms and Conditions


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