1. Cancer cells grow and divide when they should not
Mitosis – an asexual cell division, that occurs in somatic cells
“Soma” = body
Cell cycle – the “lifecycle” of the cell

2. The Cell cycle: Interphase
Interphase has three phases:
G1: cell grows, organelles duplicate
S: DNA is replicated
G2: cell makes proteins needed to complete cell division

3. DNA replication Produces exact copies of the cells chromosomes
Nucleotides are added by an enzyme called DNA Polymerase
semiconservative replication - each newly replicated DNA molecule contains a daughter and a parental DNA strand

4. Following replication, the DNA sequence ACCGTA would be paired with a daughter DNA strand with the sequence:
ACCGTA
TGGCAT
ATGCCA
UGGCAT

5. DNA replication duplicates chromosomes
Chromosomes are uncondensed before cell division
Duplicated chromosomes are called sister chromatids
They are held together at the centromere

7. The Cell cycle: Mitosis
Mitosis produces genetically-identical daughter nuclei
Four stages:
Prophase
Metaphase
Anaphase
Telophase
Mitosis is followed by cytokinesis, which splits the two nuclei into two daughter cells

8. Mitosis : Prophase and Metaphase

9. Mitosis : Anaphase and Telophase