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Chemical leukoderma. A. O-Syl (a phenolic disinfectant)-induced chemical leukoderma that mimics vitiligo clinically. Repeated exposure is required to depigment, but antecedent clinical inflammation is not observed. B. Reversible hypomelanosis of the face in a South African woman after several weeks’ application of topical hydroquinone. Note color contrast of face to that of (untreated) hand. C. African-American factory worker depigmented from repeated exposure to monobenzyl ether of hydroquinone. Source: Chapter 75. Hypomelanoses and Hypermelanoses, Fitzpatrick's Dermatology in General Medicine, 8e Citation: Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, Wolff K. Fitzpatrick's Dermatology in General Medicine, 8e; 2012 Available at: Accessed: October 29, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved
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