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Model depicting the cycling of REP
Model depicting the cycling of REP. REP binds a GDP-bound Rab and presents it to the catalytic Rab GGTα/β subunits. Upon geranylgeranylation, Rab GGT dissociates and the REP-Rab complex moves to a putative receptor which facilitates attachment of the prenylated Rab to the donor membrane. Source: Choroideremia, The Online Metabolic and Molecular Bases of Inherited Disease Citation: Valle D, Beaudet AL, Vogelstein B, Kinzler KW, Antonarakis SE, Ballabio A, Gibson K, Mitchell G. The Online Metabolic and Molecular Bases of Inherited Disease; 2014 Available at: Accessed: October 29, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved
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