1. Date: January 5th, 2017
Aim #38: How does DNA replicate itself?
HW:
Daily Review of class notes.
Packet- “DNA the Double Helix” Due Friday
Do Now:
Where is DNA found?
What determines our traits?
Where are genes located?
What part of DNA carries the genetic code?

2. Aim #38: How does DNA replicate itself?

3. 1) DNA Replication What does REPLICATE mean? (Hint)
Replicate means to make a
copy

4. 2) What do we get when DNA replicates?
Replication +
Two New
DNA Molecules

5. DNA Structure Review What is DNA composed of? Adenine Thymine Guanine
4 types
Adenine
Thymine
Guanine
Cytosine
Deoxyribose
Nucleotides

6. How do the Bases Pair Up?
H Bonds
All Teachers Go Crazy

7. 3) DNA Structure What shape is this? Double-Helix Rosalind Franklin
What scientists shared the
Nobel Prize for their work on DNA?
Maurice Wilkins
Watson & Crick
Rosalind Franklin

8. Watson and Crick (1953)
Double Helix Model: DNA consists of two twisting chains of nucleotides in a ladder-like structure
Model Explains:
How DNA replicates and how it is used to make proteins

9. Maurice Wilkins and Rosalind Franklin
used X-ray diffraction to understand the physical structure of the DNA molecule.

10. 5) What Process is Taking Place Here?
Cell Division
Why do our cells need to divide?
REPAIR
GROWTH

11. 6) What does the DNA do before a cell divides?
Genetic Information
(DNA)
DNA must replicate
before a cell divides

12. 7) Why must DNA replicate itself?
DNA is the “Blueprint” for all cell activities. Each cell needs the entire “Blueprint” to function properly.

13. 8) What are the Steps of DNA Replication?
Step 1: Bonds between the bases are broken
and the DNA Molecule is “Unzipped”
G - C
C - G
T - A
A - T
DNA
Molecule
Bonds
Broken
G C
C G
T A
A T
2 Separate
Strands
Enzymes

14. What are the Steps of DNA Replication?
Step 2: Individual bases find their “match” on
each single strand of DNA. G C T A C G A T
G C
C G
T A
A T
2 Separate
Strands G C T A C G A T
Base
Pairing
Enzymes
Each strand is a
Template for base
pairing

15. What are the Steps of DNA Replication?
Step 3: Bonds between the bases are formed
G C G C
C G C G
T A T A
A T A T
G - C G - C
C - G C - G
T - A T - A
A - T A - T
Bonds
Formed

16. DNA Replication C - G T - A A - T DNA Molecule C G T A A T 2 Separate
G - C
C - G
T - A
A - T
DNA
Molecule
G C
C G
T A
A T
2 Separate
Strands
G - C G - C
C - G C - G
T - A T - A
A - T A - T
Bonds
Broken
Base
Pairing
What is formed?
2 Identical DNA
Molecules

17. 9) Step 1: “Unzipping” the DNA
The bonds between the bases
are broken and the DNA
molecule is “Unzipped”

18. 10) Step 2: Bases Match Up
Fill in the DNA molecule below. A C G T C

19. 11) What is the final product of DNA Replication?

20. 12) Where do we find that final product?
Inside the nucleus

21. What Process is this?
DNA Replication
Each strand serves
as a Template

22. Summary Questions
Do you think DNA Replication is an accurate process? Why?
What do you think would happen if DNA did not accurately replicate?