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Objective Normal anatomy of hair follicle and hair cycle

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Presentation on theme: "Objective Normal anatomy of hair follicle and hair cycle"— Presentation transcript:

1 Objective Normal anatomy of hair follicle and hair cycle
Causes, features and management of non scarring alopecia, Particularly: Alopecia areata Androgenetic alopecia Telogen effluvium Anagen effluvium Causes and features of scarring alopecia

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4 Hair Types Vellous Terminal Androgen dependant terminal

5 Hair growth is very dynamic
Hair Cycle Hair growth is very dynamic

6 How many hairs in the body?
5 millions hairs in the body 100,000 in the scalp Growth rate? 0.3mm/day for scalp hair

7 Alopecia None Scaring (Reversible) Scaring (Irreversible)

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9 Alopecia Areata

10 Sudden hair loss ( localized or generalized)
Alopecia Areata affects up to 2% 75% : Self recovery, 2-6 m Causes : 30%: +ve Family history autoimmune

11 Clinical findings Well demarcated Exclamation point Normal scalp
Nail: pitting, ridges

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13 Types of alopecia areata - Localized partial - Localized extensive - Alopecia ophiasis - Alopecia totalis - Alopecia universalis

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16 Diagnosis Clinically H/E: sworm bees

17 Treatment 1. Observation 2. Intralesional Corticosteroids 3. Skin Sensitizers Anthraline Diphencyclopropenone (DPCP) others

18 Others Topical steroids Systemic Steroids Cytotoxic Rx Phototherapy
Minoxidil Hair Transplant – ( NO)

19 Androgenetic Alopecia (Male and Female Pattern Hair Loss)

20 Androgen dependent loss of scalp hair
Androgenetic Alopecia affects up to 50% of males and 40% of females Autosomal dominant with variable penetrance 85% : +ve family history

21 DihydorTestosterone (Active) Miniaturization of Terminal Hairs
5 ALPHA Reductase Testosterone DihydorTestosterone (Active) Miniaturization of Terminal Hairs

22 Male Pattern Hair Loss

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24 Female Pattern Hair Loss

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26 Treatment Topical: Neoxidil 2%- 5% solution Systemic: Fenastride
Spironolactone

27 Telogen effluvium Chronic alopecia Reversible (but may be become chronic) 3-4 months

28 Causes

29 Treatment Remove or treat the cause Minoxidil 2% Solution

30 Anagen effluvium Always related to cytotoxic chemotherapy
Acute and severe alopecia Mostly reversible but not always

31 Scarring Alopecia SLE—DLE LP Sarcoidosis Leprosy Kerion - Favus Trauma

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