1. Adherence in the Age of HCV Antivirals: Lessons from HIV Adherence Interventions

2. Outline

3. Introduction

4. Adherence to HCV Therapy

5. Adherence and EVR

6. Adherence and SVR

7. Adherence Over Time

8. Implications

9. Outline

10. Fluidity of Adherence Barriers

11. Risk Factors (I)

12. Risk Factors (II)

13. Provider Prediction

14. Outline

16. Adherence Interventions

17. Intervention Strategies

19. Adherence and Directly Observed Therapy (DOT)

20. Metaanalysis of DOT in HIV

21. Cellphone-Based Interventions

22. WelTel Kenya1 Results

23. Cellphone Conclusions

24. Managed Problem Solving (MAPS)

25. Defining the Problem

26. Brainstorm

27. Decision re: Plan

28. Implement Plan

29. Assessment and Modification

31. MAPS Study Design

32. Baseline Screening

33. Delivery of Intervention

34. November 2011

36. Overall Adherence Results

37. Overall VL Results

38. Conclusions and Next Steps

39. Outline

40. Intervention Lessons

41. Future Needs

42. What Should HCV Providers Do Now?

43. Conclusions

45. Acknowledgements

46. Thank you, study participants!