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Volume 138, Issue 7, Pages (June 2010)

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1 Volume 138, Issue 7, Pages 2300-2306 (June 2010)
One to 2-Year Surveillance Intervals Reduce Risk of Colorectal Cancer in Families With Lynch Syndrome  Hans F.A. Vasen, Mohamed Abdirahman, Richard Brohet, Alexandra M.J. Langers, Jan H. Kleibeuker, Mariette van Kouwen, Jan Jacob Koornstra, Henk Boot, Annemieke Cats, Evelien Dekker, Silvia Sanduleanu, Jan–Werner Poley, James C.H. Hardwick, Wouter H. de Vos tot Nederveen Cappel, Andrea E. van der Meulen–de Jong, T. Gie Tan, Maarten A.J.M. Jacobs, Faig Lall A. Mohamed, Sijbrand Y. de Boer, Paul C. van de Meeberg, Marie–Louise Verhulst, Jan M. Salemans, Nico van Bentem, B. Dik Westerveld, Juda Vecht, Fokko M. Nagengast  Gastroenterology  Volume 138, Issue 7, Pages (June 2010) DOI: /j.gastro Copyright © 2010 AGA Institute Terms and Conditions

2 Figure 1 Cumulative risk of developing colorectal cancer under surveillance in families with Lynch syndrome and non-Lynch syndrome (log rank: P < .05). The bars indicate 95% confidence intervals. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2010 AGA Institute Terms and Conditions

3 Figure 2 Cumulative risk of developing colorectal cancer under surveillance in Lynch syndrome in carriers aged 40 years or older at start of the evaluation and carriers younger than 40 years (univariate analysis: P = .08). Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2010 AGA Institute Terms and Conditions

4 Figure 3 Cumulative risk of developing colorectal cancer under surveillance in Lynch syndrome in carriers of an MLH1, MSH2, and MSH6 mutation (univariate analysis: P = .08). Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2010 AGA Institute Terms and Conditions


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