1. Anaphylaxis is likely when all of the following 3 criteria are met:
• Sudden onset and rapid progression of symptoms.
• Life-threatening Airway and/or Breathing and/or Circulation problems.
• Skin and/or mucosal changes (flushing, urticaria, angioedema)

2. (= 500 micrograms = 0.5 mL of 1:1000) adrenaline.
Adrenaline IM dose – adults:
0.5 mg IM
(= 500 micrograms = 0.5 mL of 1:1000) adrenaline.

3. Adrenaline IM dose – children
12 years: 500 micrograms IM (0.5 mL) i.e. same as adult dose
300 micrograms (0.3 mL) if child is small.

4. One ampoule of 1:1000 adrenaline in 1 ml volume.
= This equals 1mg in 1 ml.
= This equals 1000 μg/ml.

6. MCQs Penicillins & Cephalosporins

7. Which one of the following penicillins is natural
Which one of the following penicillins is natural ? A- Amoxicillin B- Ampicillin C- Cloxacillin D- Penicillin G E- Oxacillin

8. Which one of the following penicillins is used orally only
Which one of the following penicillins is used orally only? A- Amoxicillin B- Ampicillin C-Cloxacillin D-Penicillin G E-Penicillin v

9. Which one of the following penicillins is anti staphylococcal
Which one of the following penicillins is anti staphylococcal? A-Amoxicillin B-Ampicillin C-Cloxacillin D-Penicillin G E-Penicillin v

10. All the following drugs are beta lactam antibiotics except: A- Amoxicillin B- Ampicillin C- Cloxacillin D- Imipenem E- Vancomycin.

11. Which one of the following penicillins is anti pseudomonal
Which one of the following penicillins is anti pseudomonal? A-Amoxicillin B-Carbinicillin C-Cloxacillin D- Imipenem E-Vancomycin.

12. Which one of the following penicillins is not effective against gram negative bacteria? A-Amoxicillin B-Carbinicillin C-Cloxacillin D- Imipenem E-Ampicillin.

13. Which one of the following drugs is an Injectable cephalosporin which has half life of 8 hours and excreted in the bile? A- Cephalexin B- Cefaclor C- Ceftriaxone D- Cefuroxime E- Cefixime

14. Which one of the following drugs is first generation cephalosporin
Which one of the following drugs is first generation cephalosporin? A- Cephalexin B- Cefaclor C- Ceftriaxone D- Cefuroxime E- Cefixime

15. Which one of the following drugs is a second generation cephalosporin
Which one of the following drugs is a second generation cephalosporin? A- Cephalexin B- Cephalothin C- Ceftriaxone D- Cefuroxime E- Cefixime

16. Which one of the following antibiotics is not broad spectrum
Which one of the following antibiotics is not broad spectrum? A- Ampicillin. B- Cloxacillin C- Ceftriaxone D- Amoxicillin E- Cephalexin.

17. Which one of the following drugs is not used systemically
Which one of the following drugs is not used systemically? A- Cephalexin. B- Cephalothin. C- Bacitracin. D- Vancomycin. E- Cefixime.

18. Concerning penicillins all the followings are true except
Concerning penicillins all the followings are true except? A-Penicillin g is given Parenterally. B- Ampicillin is better absorbed than amoxicillin. C-penicillin v is given orally. D-procaine penicillin is given IM. E- Piparacillin is an anti pseudomonal drug.

19. All of the following drugs can be injected intravenously except: A- Ceftriaxone B- Cefotaxime C- Cefuroxime Axetil D- Benzathine Penicillin E- Penicillin G

20. Which one of the following drugs has the best activity against Penicillinase producing gram negative bacteria? A- Ampicillin B- Oxacillin C- Ampicillin + Cloxacillin D- Amoxicillin + Clavulanic acid E- Cefuroxime axetil

21. Concerning cephalosporins all the following are true except:
A- First generation cephalosporins have better activity on gram positive bacteria than third generation.
B- Cephalexin cab be used to treat soft tissue infections
C- Ceftriaxone is used in serious infections
D- Cefotaxime is used by injections
E- Cefuroxime axetil is not effective agaist gram negative bacteria.

22. Which one of the following drugs can be used safely in patients with severe allergy to penicillins?
A-Ceftriaxone
B-Aztreonam
C-Vancomycin
D- Imipenem
E- Cefuroxime axetil.

23. Which one of the following drugs is not a beta lactam antibiotic
Which one of the following drugs is not a beta lactam antibiotic? A-Meropenem B-Carbinicillin C-Ceftriaxone D-Vancomycin E-Ticarcillin

24. Which one of the following drugs is known to induce toxic skin rash in EB virus infection? A- Cephalexin B- Ceftriaxone C- Ampicillin D- Vancomycin E- Clindamycin

25. Which one of the following antibiotics is not useful in treating UTI
Which one of the following antibiotics is not useful in treating UTI? A- Cephalexin. B- Procaine Penicillin. C- Cefuroxime. D- Ceftriaxone. E- Cefixime.

26. What is the most serious adverse reaction to penicillin
What is the most serious adverse reaction to penicillin? How Can you avoid it?

27. You are working in an outpatient clinic where you were asked to manage a patient with fever(temp 39), you diagnosed his condition as acute tonsillitis. You prescribed procaine penicillin 1,200,000 iu twice daily IM Following the injection you were asked to urgently resuscitate the patient as he loosed consciousness and fell on the ground. What are the possible causes? How are you going to manage this patient?

28. You are working as a resident physician at a medical word, you ere asked to see a patient who developed vomiting after an intravenous antibiotic. How are you going to think?

29. A patient with meningitis and suspected allergy to penicillin is in need of effective intravenous beta lactam antibiotic. Which drug are you going to choose? How are you going to administer the drug?