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Ocular Features of West Nile Virus Infection in North America
Clement K. Chan, MD, FACS, Scott A. Limstrom, MD, Dariusz G. Tarasewicz, MD, PhD, Steven G. Lin, MD Ophthalmology Volume 113, Issue 9, Pages (September 2006) DOI: /j.ophtha Copyright © 2006 American Academy of Ophthalmology Terms and Conditions
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Figure 1 Patient 2. A, Fundus examination revealed multiple cream-colored chorioretinal lesions (arrowheads), focal retinal hemorrhage, and ischemia superior to the disc in the left eye that highlight the partially active multifocal chorioretinal lesions in this 71-year-old woman with West Nile virus infection (subacute stage). B, Corresponding fluorescein angiogram showed hypofluorescence and a surrounding ring of hyperfluorescence (arrowheads) on the chorioretinal lesions superior to the disc of the left eye (subacute stage). C, Arterial narrowing, perivascular sheathing, and vascular occlusion (arrowheads) were found on the posterior and midperipheral fundus, both superior and inferior to the disc, of the right eye. Ophthalmology , DOI: ( /j.ophtha ) Copyright © 2006 American Academy of Ophthalmology Terms and Conditions
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Figure 2 A, Anterior segment examination results of patient 3 show perivascular sheathing with occlusive vasculitis, optic pallor, and numerous dot and blot hemorrhages on the superior and posterior fundus of the right eye of this 58-year-old diabetic woman with West Nile virus infection. B, Anterior segment examination of the left eye of patient 4, a 32-year-old man with West Nile virus infection, shows multiple intraretinal hemorrhages and adjacent perivascular sheathing involving multiple venous tributaries. Ophthalmology , DOI: ( /j.ophtha ) Copyright © 2006 American Academy of Ophthalmology Terms and Conditions
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Figure 3 A, Anterior segment examination results of patient 5, a 55-year-old Hispanic man with type 2 diabetes mellitus and West Nile virus infection, showing multiple active (arrow) and partially active (arrowhead) discrete cream-colored chorioretinal spots (100–300 μm) on the posterior and peripheral fundus of the left eye (acute and subacute stages). B, The corresponding fluorescein angiogram examination showed early hypofluorescence (arrow) on the active chorioretinal spots (acute stage) and focal hypofluorescence with a surrounding hyperfluorescent ring (arrowhead) on the partially active lesions (subacute stage). Subsequent images in the late phase of the same angiogram showed staining of the active lesions. Ophthalmology , DOI: ( /j.ophtha ) Copyright © 2006 American Academy of Ophthalmology Terms and Conditions
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Figure 4 Patient 6. A, Dilated fundus examination of the right eye of this 68-year-old diabetic woman with West Nile virus infection showed multifocal inactive chorioretinal atrophic lesions with a distinct margin (arrowheads; convalescent stage). B, Dilated fundus examination of the left eye showed similar chorioretinal atrophic lesions (arrowhead) and whitish-yellow chorioretinal linear streaks (arrow) on inferior midperipheral fundus. C, D, Fluorescein angiogram examination showed persistent focal hyperfluorescence of the same lesions throughout the study. Ophthalmology , DOI: ( /j.ophtha ) Copyright © 2006 American Academy of Ophthalmology Terms and Conditions
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