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Colistin for the treatment of ventilator-associated pneumonia caused by multidrug- resistant Gram-negative bacteria: A systematic review and meta-analysis 

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Presentation on theme: "Colistin for the treatment of ventilator-associated pneumonia caused by multidrug- resistant Gram-negative bacteria: A systematic review and meta-analysis "— Presentation transcript:

1 Colistin for the treatment of ventilator-associated pneumonia caused by multidrug- resistant Gram-negative bacteria: A systematic review and meta-analysis  Wan-Jie Gu, Fei Wang, Lu Tang, Jan Bakker, Jing-Chen Liu  International Journal of Antimicrobial Agents  Volume 44, Issue 6, Pages (December 2014) DOI: /j.ijantimicag Copyright © 2014 Elsevier B.V. and the International Society of Chemotherapy Terms and Conditions

2 Fig. 1 Flow diagram of the selection process of the included studies. AS, aerosolised; IV, intravenous. International Journal of Antimicrobial Agents  , DOI: ( /j.ijantimicag ) Copyright © 2014 Elsevier B.V. and the International Society of Chemotherapy Terms and Conditions

3 Fig. 2 Forest plot depicting clinical cure. AS, aerosolised; IV, intravenous. International Journal of Antimicrobial Agents  , DOI: ( /j.ijantimicag ) Copyright © 2014 Elsevier B.V. and the International Society of Chemotherapy Terms and Conditions

4 Fig. 3 Forest plot depicting microbiological eradication. AS, aerosolised; IV, intravenous. International Journal of Antimicrobial Agents  , DOI: ( /j.ijantimicag ) Copyright © 2014 Elsevier B.V. and the International Society of Chemotherapy Terms and Conditions

5 Fig. 4 Forest plot depicting intensive care unit mortality. AS, aerosolised; IV, intravenous. International Journal of Antimicrobial Agents  , DOI: ( /j.ijantimicag ) Copyright © 2014 Elsevier B.V. and the International Society of Chemotherapy Terms and Conditions

6 Fig. 5 Forest plot depicting hospital mortality. AS, aerosolised; IV, intravenous. International Journal of Antimicrobial Agents  , DOI: ( /j.ijantimicag ) Copyright © 2014 Elsevier B.V. and the International Society of Chemotherapy Terms and Conditions

7 Fig. 6 Forest plot depicting the length of intensive care unit stay. AS, aerosolised; IV, intravenous. International Journal of Antimicrobial Agents  , DOI: ( /j.ijantimicag ) Copyright © 2014 Elsevier B.V. and the International Society of Chemotherapy Terms and Conditions

8 Fig. 7 Forest plot depicting nephrotoxicity. AS, aerosolised; IV, intravenous. International Journal of Antimicrobial Agents  , DOI: ( /j.ijantimicag ) Copyright © 2014 Elsevier B.V. and the International Society of Chemotherapy Terms and Conditions

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