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Cardiovascular Outcomes Trials in Diabetes: The Truth, the Whole Truth, and Nothing But the Truth
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Program Goals
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The Growing Diabetes Pandemic
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Approved Antidiabetic Medications
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Cardiovascular benefits to tighter HbA1c control?
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Outcomes of Better Glycemic Control in T2D: UKPDS and Post-UKPDS
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Should Hyperglycemia in Diabetes Be Treated Aggressively?
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DCCT/EDIC: Intensive Diabetes Therapy in T1D
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Counseling a Patient With Newly Diagnosed T2D
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Sulfonylureas
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Safety of Sulfonylureas
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Safety of Sulfonylureas (cont)
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The CAROLINA Study: Phase 3 Results
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Rosiglitazone Data Reanalyzed
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Results of a Reevaluation of Cardiovascular Outcomes in the RECORD Trial
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Thiazolidinediones
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Pioglitazone: The PROactive Study
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Guidance for Industry: Diabetes Mellitus -- Evaluating Cardiovascular Risk in New Antidiabetic Therapies to Treat T2D
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Impact of FDA Guidance: December 2008
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Incretin-Based Drugs
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Incretin-Based Drugs (cont)
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Warnings and Precautions
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SGLT-2 Inhibitors
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SGLT-2 Inhibitors (cont)
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SAVOR-TIMI 53 trial
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Take-Home Messages
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Abbreviations
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Abbreviations (cont)
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Abbreviations (cont)
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References
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References (cont)
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References (cont)
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References (cont)
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References (cont)
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References (cont)
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References (cont)
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References (cont)
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