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Simultaneous positron emission tomography (PET) assessment of metabolism with 18F- fluoro-2-deoxy-d-glucose (FDG), proliferation with 18F-fluoro-thymidine.

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Presentation on theme: "Simultaneous positron emission tomography (PET) assessment of metabolism with 18F- fluoro-2-deoxy-d-glucose (FDG), proliferation with 18F-fluoro-thymidine."— Presentation transcript:

1 Simultaneous positron emission tomography (PET) assessment of metabolism with 18F- fluoro-2-deoxy-d-glucose (FDG), proliferation with 18F-fluoro-thymidine (FLT), and hypoxia with 18fluoro-misonidazole (F-miso) before and during radiotherapy in patients with non-small-cell lung cancer (NSCLC): A pilot study  Pierre Vera, Pierre Bohn, Agathe Edet-Sanson, Alice Salles, Sebastien Hapdey, Isabelle Gardin, Jean-François Ménard, Romain Modzelewski, Luc Thiberville, Bernard Dubray  Radiotherapy and Oncology  Volume 98, Issue 1, Pages (January 2011) DOI: /j.radonc Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions

2 Fig. 1 Actual schedule for the five evaluable patients.
Radiotherapy and Oncology  , DOI: ( /j.radonc ) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions

3 Fig. 2 SUVmax for FLT, FDG, and F-miso before and during radiotherapy (RT) for 4 tumours and 12 nodes. Symbols represent the mean SUVmax. Error bars are 2× the standard error of the mean (SEM). Radiotherapy and Oncology  , DOI: ( /j.radonc ) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions

4 Fig. 3 Correlations between the tracers’ uptakes.
Radiotherapy and Oncology  , DOI: ( /j.radonc ) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions

5 Fig. 4 Example of patient #003. Patient having 1 primary tumor and 4 mediastinal nodes [1 node is not presented at 46Gy (superimposition)]. Radiotherapy and Oncology  , DOI: ( /j.radonc ) Copyright © 2010 Elsevier Ireland Ltd Terms and Conditions


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