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Recurrent infective endocarditis causing heart valve failure: A case report  Victoria McIntyre, BASc Chemical Engineering (2018 candidate), Jagdish Butany,

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Presentation on theme: "Recurrent infective endocarditis causing heart valve failure: A case report  Victoria McIntyre, BASc Chemical Engineering (2018 candidate), Jagdish Butany,"— Presentation transcript:

1 Recurrent infective endocarditis causing heart valve failure: A case report 
Victoria McIntyre, BASc Chemical Engineering (2018 candidate), Jagdish Butany, MBBS, MS, FRCPC, Dina Boles, MD, Tiffany Shao, MD  Human Pathology: Case Reports  Volume 10, Pages (November 2017) DOI: /j.ehpc Copyright © Terms and Conditions

2 Fig. 1 Explanted bioprosthetic porcine valve (EPIC®, SJM, Minneapolis, USA) at 18months. The flow surface shows thrombus (arrow) on the valve's leaflets. Human Pathology: Case Reports  , 39-42DOI: ( /j.ehpc ) Copyright © Terms and Conditions

3 Fig. 2 Explanted bioprosthetic porcine valve (EPIC®, SJM, Minneapolis, USA) at 18months. The non-flow surface has pannus (P) on the sewing cuff extending onto the leaflets as well as large vegetations (arrow) on the cusps and in the sinuses. Human Pathology: Case Reports  , 39-42DOI: ( /j.ehpc ) Copyright © Terms and Conditions

4 Fig. 3 Transverse sections through the commissural region of the bioprosthesis shows the junction of two cusps (black arrows), suture sites (black broken arrows) and the commissural end of the cusps (C). Pericardium (P) covers the porcine aortic tissue (A). (Original magnification ×2.5; Movat pentachrome stain) Human Pathology: Case Reports  , 39-42DOI: ( /j.ehpc ) Copyright © Terms and Conditions

5 Fig. 4 The porcine bioprosthetic cusp showing vegetations (arrows), pannus (broken arrow), pericardium (P) and porcine aortic root (A). (Original magnification ×1.25; Movat pentachrome stain) Human Pathology: Case Reports  , 39-42DOI: ( /j.ehpc ) Copyright © Terms and Conditions

6 Fig. 5 The valve displaying small foci of calcification (arrows). Calcification is largely in the deeper parts of the thrombotic vegetations on the cusps. (Original magnification ×10; H&E) Human Pathology: Case Reports  , 39-42DOI: ( /j.ehpc ) Copyright © Terms and Conditions

7 Fig. 6 The porcine bioprosthesis demonstrating the presence of colonies of Gram positive bacterial cocci (arrows). (Original magnification ×5; GMS) Human Pathology: Case Reports  , 39-42DOI: ( /j.ehpc ) Copyright © Terms and Conditions

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