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Enzymes and drugs P450 enzymes breakdown/metabolize active drug

Published byHester Bailey Modified over 6 years ago

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Presentation on theme: "Enzymes and drugs P450 enzymes breakdown/metabolize active drug"— Presentation transcript:

1

2 Enzymes and drugs P450 enzymes breakdown/metabolize active drug
Inactive drug P450 enzymes breakdown/metabolize active drug

3 Inhibitors slow the enzyme Increase drug concentration
P450 enzymes P450 enzymes P450 enzymes Inhibitors slow p450 Active Drug is increased Inhibitors slow the enzyme Increase drug concentration

4 Enzymes and drugs INDUCERS - ↑↑↑↑ metabolism
Active Drug is decreased Inducers Speed p450 Inducers increased metabolism Reduce drug concentration

5 Enzymes and drugs Inhibit0rs- ↓↓↓ metabolism
Inducers increased the enzyme Reduce drug concentration

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