1. Blood Typing

2. Blood Typing
Human Blood comes in a variety of genetically determined blood groups.
Knowing a person’s blood group is critical
If a medical procedure is done and the wrong blood is used, things could become fatal.
Multiple genes are responsible for blood groups (ABO)
Single gene for the Rh blood group

3. Codominance Equal dominance human ABO blood groups 3 version
A, B, i
A & B alleles are codominant
both A & B alleles are dominant over i allele
the genes code for different sugars on the surface of red blood cells
“name tag” of red blood cell

4. Genetics of Blood type A A A or A i B BB or B i AB O i i pheno-type
genotype
antigen on RBC
antibodies in blood
donation status A
A A or A i
type A antigens on surface of RBC
anti-B antibodies __ B
BB or B i
type B antigens on surface of RBC
anti-A antibodies AB
both type A & type B antigens on surface of RBC
no antibodies
universal recipient O
i i
no antigens on surface of RBC
anti-A & anti-B antibodies
universal donor

5. Blood donation clotting clotting clotting clotting clotting clotting