1. Sildenafil in severe pulmonary hypertension associated with chronic obstructive pulmonary disease: A randomized controlled multicenter clinical trial 
Patrizio Vitulo, MD, Anna Stanziola, MD, Marco Confalonieri, MD, Daniela Libertucci, MD, Tiberio Oggionni, MD, Paola Rottoli, MD, Giuseppe Paciocco, MD, Fabio Tuzzolino, BS, PhD, Lavinia Martino, MD, Marta Beretta, MD, Adriana Callari, MD, Andrea Amaducci, MD, Roberto Badagliacca, MD, Roberto Poscia, MD, Federica Meloni, MD, Rosa Metella Refini, MD, Pietro Geri, MD, Sergio Baldi, MD, Stefano Ghio, MD, Michele D’Alto, MD, PhD, Paola Argiento, MD, PhD, Matteo Sofia, MD, Mara Guardamagna, BA(Econ), Beatrice Pezzuto, MD, Carmine Dario Vizza, MD 
The Journal of Heart and Lung Transplantation 
Volume 36, Issue 2, Pages (February 2017)
DOI: /j.healun
Copyright © 2016 International Society for Heart and Lung Transplantation Terms and Conditions

2. Figure 1
Flow chart of patient disposition in the study. 6’WT, 6-minute walk test; COPD, chronic obstructive pulmonary disease; ITT, intention to treat; PCWP, pulmonary capillary wedge pressure; PH, pulmonary hypertension; RHC, right-heart catheterization; sPAP, systolic pulmonary artery pressure; TTE, transthoracic echocardiography.
The Journal of Heart and Lung Transplantation  , DOI: ( /j.healun )
Copyright © 2016 International Society for Heart and Lung Transplantation Terms and Conditions

3. Figure 2
Plot of mean pulmonary artery pressure (mPAP) against forced expiratory volume in 1 second (FEV1) of the patients at baseline right-heart catheterization.
The Journal of Heart and Lung Transplantation  , DOI: ( /j.healun )
Copyright © 2016 International Society for Heart and Lung Transplantation Terms and Conditions

4. Figure 3
Primary and secondary end point variables significantly varied in patients treated with sildenafil (see also Tables 2–4). The error bars indicate the standard deviation. BODE, body mass index, airflow obstruction, dyspnea, and exercise capacity; CI, cardiac index; Dlco, diffusion capacity of the lung for carbon monoxide; PPVR, peripheral pulmonary vascular resistance.
The Journal of Heart and Lung Transplantation  , DOI: ( /j.healun )
Copyright © 2016 International Society for Heart and Lung Transplantation Terms and Conditions

5. Figure 4
Trend of rest peripheral capillary oxygen saturation (Spo2) at the scheduled visits
The Journal of Heart and Lung Transplantation  , DOI: ( /j.healun )
Copyright © 2016 International Society for Heart and Lung Transplantation Terms and Conditions