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Why is blood so important to survival?
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Bleeding Stories Anyone?
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Why is blood so important to survival?
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Functions of Blood transport medium protection (immunity) regulation
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What is blood made of?
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What are the four main parts of blood?
Red blood cells White blood cells Platelets Plasma
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(as a cell, tissue, organ, or organ system?)
How would blood be classified? (as a cell, tissue, organ, or organ system?)
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blood - a fluid tissue composed of plasma in which RBC's, WBC's, and platelets are suspended
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Red Blood Cells
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There are 5,000,000 red blood cells in one drop (1 microliter) of blood
There are about 5 liters of blood in the body. How many red blood cells are there in the body?
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There are 25,000,000,000,000 red blood cells in the human body.
If 3 million red blood cells die each second, then how many must be made to replace them in one day? 259,200,000,000
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Development of Red Blood cells
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Bone Marrow
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Why do red blood cells have this shape?
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Side view of a red blood cell
oxygen carbon dioxide (blood vessel in lungs)
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Side view of a red blood cell
oxygen carbon dioxide (blood vessel in tissues)
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How is a red blood cell like a taxi?
oxygen Tissues Lungs Carbon dioxide
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1 2 1 - Oxygen, nutrients, hormones CELLS IN BODY BLOOD
1 – metabolic wastes including Carbon dioxide, hormones
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red blood cell
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Hemoglobin
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Hemoglobin a complex iron-containing protein that carries oxygen and carbon dioxide throughout the body and gives blood its red color
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Sickled Cell
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Anemia Decreased ability of the red blood cells to provide adequate oxygen supplies to body tissues.
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Sickle-cell anemia: an inherited, potentially lethal disease in which a defect in hemoglobin, the oxygen-carrying pigment in the blood, causes distortion (sickling) and loss of red blood cells, producing damage to organs throughout the body.
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Causes of Anemia abnormal hemoglobin insufficient amount of hemoglobin
insufficient amount of red blood cells Causes - dietary deficiency - premature destruction of red blood cells
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White Blood Cells
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Immune Cells
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White Blood Cells protect the body from pathogens
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phagocytosis http://www.youtube.com/watch?v=fpOxgAU5fFQ
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Centrifuge
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Plasma clear straw-colored liquid portion of the blood 90% water
10% dissolved substances Glucose, Salts, Amino Acids, Fatty Acids, Vitamins, Enzymes, Hormones, Cellular Wastes, Proteins
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Regulate blood clotting
Plasma Proteins Albumin Prevents water from leaving blood and entering cells Clotting Factors Regulate blood clotting Globulins Transporters, Antibodies
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Concept Map Wordbank Water Hemoglobin Platelets White Blood Cells
Anemia Clotting factors Immunity Oxygen Carbon Dioxide Blood Clotting Plasma Red Blood Cells
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Blood Cells Cell Fragments 1. _____ 2. _____ 3. ______ 5. ______
Directions: Use the word bank on the following page and the pages in your text to fill in the missing words. Blood contains Cells Cell Fragments 1. _____ is mostly also contains such as called 2. _____ 3. ______ 5. ______ 6. ________ 4. ______ contain too few causes functions in 7. ___________ needed for 9. _________ 8. ______ 10. ____________ which carries 11. ______ 12. _________
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Blood Cells Cell Fragments 1. Plasma 2. RBCs 3. WBCs 5. Water
6. Clotting factors 4. Platelets 7. hemoglobin 9. immunity 8. anemia 10. Blood clotting 11. oxygen 12. Carbon dioxide
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What is this?
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How do blood clots form?
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Clotting Animation http://health.howstuffworks.com/adam-200077.htm
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Platelets
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Platelets Adhere (attach) to the walls of broken blood vessels (sealant) Adhere to each other to help establish a clot Release chemicals which stimulate the blood to clot
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A Blood Clot Forming 1 platelet 2 fibrin 3 Red blood cell
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The Process of Blood Clotting
Blood vessel injured Platelets release Thromboplastin Prothrombin Thrombin Fibrinogen Fibrin Fibrin Net traps Platelets and Red Blood cell to form clot
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The Process of Blood Clotting
When a blood vessel is injured, platelets in the blood release a protein (fibrin) that forms a net This net traps blood cells and platelets forming a blood clot
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Coronary Thrombosis
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How are blood clots dissolved?
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What do these creatures have in common?
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substances that prevent clot formation
anticoagulants substances that prevent clot formation - heparin - used as a drug after surgery to prevent clotting
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Imagine that you could create an ideal artificial blood
Imagine that you could create an ideal artificial blood. Describe some of the characteristics you would want it to have.
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Blood pH to 7.45!!!
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CO2 + H2O H2CO3 Carbonic acid H+ + HCO3- Bicarbonate ion Carbonic
anhydrase H2CO3 Carbonic acid H+ + HCO3- Bicarbonate ion In lungs In tissues
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