1. Selective Laser Trabeculoplasty (SLT) as replacement therapy
De Keyser M 1, De Belder M 2, De Groot V 1,3.
1, University of Antwerp, dep. Medicine, Belgium; 2, University of Ghent, dep. Experimental
Psychology, Belgium; 3, Antwerp University Hospital, dep. Ophthalmology, Belgium
Introduction
Material and Methods
Glaucoma remains a chronical disease. Decades of taking topical medication influences ocular surface and quality of life. Diminishing adherence to the local therapy can lead to disease progression.
Selective laser trabeculoplasty (SLT) has proven its value as a primary therapy and as adjuvant therapy in glaucoma and ocular hypertension.
We examined if SLT could be used
as replacement therapy
in glaucoma patients
controlled under medication.
Laser technique:
Q-switched Nd:YAG
spots over 360°
1.1 ± 0.3mJ
Randomized Prospective Clinical Trial 143 patients
Inclusion criteria:
- primary open angle glaucoma (POAG)
ocular hypertension
controlled intraocular pressure (IOP) with medication
Exclusion criteria:
- other glaucoma than POAG
- previous trabeculectomy or trabeculoplasty
Methods:
- registration of IOP
- measurement of number of medication
after 1h, 1w, 1, 3, 6 and 12m
Results
Conclusions
1. SLT maintained good IOP control
No change in control group
SLT maintains good IOP control
SLT reduces amount of medications needed
74% of patients no longer needed any medication after 12m
22% needed one medication after 12m
2. SLT lowered # of medications needed
No change in control group
We have no conflict of interest to disclose
References
Fechtner RD, Godfrey DG, Budenz D, Stewart JA, Stewart WC & Jasek MC (2010): Prevalence of Ocular Surface Complaints in Patients With Glaucoma Using Topical Intraocular Pressure–Lowering Medications. Cornea 29:
2. Baudouin C. Detrimental effect of preservatives in eyedrops: implications for the treatment of glaucoma. Acta Ophthalmologica. 2008;86(7):716–726. doi: /j x. 
3. Francis BA, Ianchulev T, Schofield JK & Minckler DS (2005): Selective laser trabeculoplasty as a replacement for medical therapy in open-angle glaucoma. Am J Ophthalmol 140: 524–525.
4. Francis BA, Loewen N, Hong B, et al. (2016): Repeatability of selective laser trabeculoplasty for open-angle glaucoma. BMC Ophthalmol 16: 128.
5. Katz LJ (2015): Selective Laser Trabeculoplasty Versus Medical Therapy as Initial Treatment of Glaucoma. J Glaucoma 21: