1. Viruses
MARCUS MEHTA

2. Small – EM, contain proteins, +- lipids NO ORGANELLES
“To compare the differences in biological and physical properties between viruses & bacteria”
Small – EM, contain proteins, +- lipids
NO ORGANELLES
Obligate intracellular parasites
Viral replication- following entry
DNA viruses replicate in the nucleus, RNA viruses replicate in the cytoplasm

3. “List the essential components of viruses, and their functions”
NUCLEIC ACID
-DNA ds or ss, circular or linear
-RNA ds or ss (ss may be +ve/-ve), linear or segmented
PROTEINS
-Allow viral function (Capsid,Attachment,Enzymes,Prevent apoptosis)
LIPID ENVELOPE
-No envelope-no infectivity
-contains external attachment proteins

4. Classified according to: -Genetic material -Capsid nature -Enveloped?
“Outline the basis of viral classification into families, genera, and strains”
Classified according to:
-Genetic material
-Capsid nature
-Enveloped?
-Size and shape

5. “Describe the main steps involved in viral replication”
SIX STEPS:
Attachment
Entry
Uncoating
Macromolecular synthesis
Assembly
Release

6. VIRION-virus particles (the 3 components)
“Define the terms: virion; genome; capsid; envelope; positive and negative polarity of RNA; viral tropism; the Baltimore classification of viral replication; reverse transcriptase; retrovirus”
VIRION-virus particles (the 3 components)
Genome-the viruses hereditary info
Viral tropsim-Specificity of a virus for a host tissue
Baltimore classification- 7 classes seperated based on their type of genome & replication method
Reverse transcriptase- DNA polymerase enzyme that transcribes single-stranded RNA into single-stranded DNA
Retrovirus-Use reverse transcriptase. Convert their RNA genomes to DNA then integrate