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Medical Neuroscience Dr. Wiegand

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1 Medical Neuroscience Dr. Wiegand
Brainstem I Medical Neuroscience Dr. Wiegand

2 Brainstem Lectures Brainstem I Brainstem II External structure
Cerebellum Cranial nerves Brainstem II Internal structure Cranial nerve nuclei Reticular formation Location of selected tracts

3 Brainstem Organization
tectum tegmentum basis pyramid midbrain pons medulla oblongata cerebellum

4 Ventral Brainstem Cerebral peduncles Interpeduncular fossa
Basilar pons Pyramids & decussation Olives Anterior median fissure Olivary sulci Bulbopontine sulcus Cerebellar angle

5 Dorsal Brainstem Colliculi & brachia Cerebellar peduncles
Rhomboid fossa Tuberculum Gracilis Tuberculum Cuneatus Tuberculum Cinereum

6 “Open” vs. “Closed” Medulla

7 Dorsal Brainstem – Rhomboid Fossa
Isthmus Velum Obex Posterior median sulcus Medial eminence Facial colliculus Sulcus limitans Stria Medullares Trigones Hypoglossal Vagal

8 Cerebellum Outgrowth of pons
Connects to brainstem through cerebellar peduncles Functions Muscle tone regulation Coordinated movement Postural control Motor learning

9 Cerebellum Cerebellar cortex surrounding white matter
Series of fissures and folia

10 Cerebellum Anterior lobe Fissures Floculonodular lobe Posterior lobe
Tonsils Vermis

11 Cranial Nerve Functional Classifications
GSE – motor innervation of somatic musculature SVE – motor innervation of branchiomeric musculature GVE – motor innervation of viscera GVA – sensory input from viscera SVA – taste and smell sensory input GSA – general somatosensory input SSA – special senses of vision and hearing/balance

12 I II III IV V VI VIII VII IX XII X XI

13 Cranial Nerves – Telencephalon & Diencephalon
I, II Cranial Nerves – Telencephalon & Diencephalon Olfactory – smell (SVA) Optic – vision (SSA)

14 Cranial Nerves – Mesencephalon
III, IV Cranial Nerves – Mesencephalon Oculomotor – extraocular eye muscles (GSE) PSNS to eye (GVE) Trochlear – extraocular muscle (sup. oblique) (GSE)

15 Cranial Nerves – Metencephalon
V, VI Cranial Nerves – Metencephalon Trigeminal – Muscles of mastication (SVE) General sensation of the head and face (GSA) Abducens – extraocular muscle (lat. rectus) (GSE)

16 Cranial Nerves – Metencephalon
VII, VIII Cranial Nerves – Metencephalon Facial – Facial expression muscles (SVE) Glands (submandibular, sublingual & lacrimal) (GVE) Taste (SVA) General sensation of ear (GSA) Vestibulocochlear – Hearing and balance (SSA)

17 Cranial Nerves – Mylencephalon
IX Cranial Nerves – Mylencephalon Glossopharyngeal Stylopharyngeus muscle (SVE) PSNS to parotid gland (GVE) Taste (SVA) Carotid body sensation (GVA) General sensation from ear & tongue (GSA)

18 Cranial Nerves – Mylencephalon
X Cranial Nerves – Mylencephalon Vagus Muscles of larynx & pharynx (SVE) PSNS to thorax and upper abdomen (GVE) Sensory from viscera (GVA) General sensation from ear (GSA) Taste (SSA)

19 Cranial Nerves – Mylencephalon
XI, XII Cranial Nerves – Mylencephalon Accessory – innervates trapezius and sternocleidomastoid (SVE or GSE) Hypoglossal – tongue muscles (GSE)

20 Cranial Nerve Groups Parasympathetic Motor Sensory Mixed
III, VII, IX, X Motor III, IV, VI, XI, XII Sensory I, II, VIII Mixed V, VII, IX, X

21 Descending Pathway Pyramidal or Corticospinal

22 Ascending Pathways Dorsal Column/Medial Lemniscal Pathway
Anterolateral System Spinocerebellar Tracts

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