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Fig. 2. Quantitative assessment of axonal damage: effects of SPD 502

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1 Fig. 2. Quantitative assessment of axonal damage: effects of SPD 502
Fig. 2. Quantitative assessment of axonal damage: effects of SPD 502. The total APP scores were derived from scoring of presence or absence of APP-positive axons at the 65 predefined neuroanatomic locations in vehicle- and SPD 502–treated groups. SPD 502 significantly reduced axonal damage detected by APP accumulation compared with the vehicle-treated group. Each point represents an individual animal, and the horizontal bar indicates the median. APP, amyloid precursor protein. **P < 0.01, two-tailed Mann-Whitney test. Published in: Eileen McCracken; Jill H. Fowler; Deborah Dewar; Steve Morrison; James McCulloch; J Cereb Blood Flow Metab  22, DOI: / Copyright © 2002 International Society for Cerebral Blood Flow and Metabolism


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