1. PRISM-PLUS: Demographics of Patients With Diabetes
Patients Without Patients With
Diabetes Diabetes
(n=1208) (n=362)
Mean age (y)
Prior MI 40% 47%
Heart failure 7% 16%
PTCA 31% 28%
CABG 23% 24% 1

2. PRISM-PLUS: MI/Death Outcomes in Patients With Diabetes
19.2% 5 15 10 20
15.5%
P=0.004
11.2%
% Patients
9.3%
4.7%
1.2%
Day 7
Day 30
Day 180 2

3. PRISM-PLUS: MI in Patients With Diabetes5 15 10 20
P=0.008
P=0.002
13.5%
P<0.001
11.4%
% Patients
7.8%
4.7%
1.8% 0%
Day 7
Day 30
Day 180 3

4. PRISM-PLUS: Results in Patients With Diabetes
Conclusion
Tirofiban + heparin therapy resulted in a marked sustained reduction in major cardiac outcomes, particularly recurrent MI, in patients with diabetes presenting with UAP/NQWMI. 4