2. Indications of surgery in ulcerative colitis
Dr. Maryam SAEI NAEIMI
KISH- 18 ESFAND 1395

3. The Overall Incidence of Colectomy in a UC Patient Ranges from 23% to 45%

4. Incidication for Colectomy
Acute flare unresponsive to medical measures
Intravenous Steroid
Bowel Rest
Parenteral hyper alimentation
Cyclosporine

5. Development of a Life-threatening complications
Toxic colitis
Perforation
Hemorrhage

6. Medical intractability
Is the most common indication for operation and may seem difficult to define.
12 months of Steroids or other immunosuppressive management without complete resolution of symptoms is an adequate medical trial.

7. Risk of Malignancy
The risk of cancer is relatively low for the first 10 years after disease onset then begins to increase at a rate of 1%-2% per year.
Low grade dysplasia
High grade dysplasia
Carcinoma

8. Disabling extra colonic disease
Arthritis
Uveitis or Iritis
Primary sclerosing cholangitis
Ankylosing spondylitis
Sacroiliitis
Pyoderma gangrenosum

9. Growth retardation in children
Steroid therapy
Inadequate protein intake and excess loss in the colon
Rapid growth spurt is often observed after definitive surgery.