1. An Introduction to the Nervous System (Dosman)
Organization and nerve cells

2. What is the nervous system?
A network of specialized cells throughout your body that carry electrochemical messages from one part of the body to another.
Interacts with the endocrine system to maintain homeostasis.
Nervous system works much faster than the endocrine system (electrochemical messages relayed by the brain versus chemical messages carried in the blood.

3. Divisions of the Nervous System
Central Nervous System (CNS): consists of the brain and spinal cord.
CNS is the control center for the body, actions (and messages) must pass through the CNS before being performed.
Peripheral Nervous System (PNS): all other parts of the nervous system. Relays info between the CNS and other parts of the body.

4. Divisions of the Nervous System
The PNS can be divided further into the somatic nervous system and the autonomic nervous system.
The somatic nervous system controls voluntary movements of the body involving the skeletal muscles, bones and skin. It includes motor and sensory neurons.
The autonomic nervous system is responsible for involuntary actions of the body and contains special motor nerves that control the internal organs of the body. Includes two divisions, sympathetic and parasympathetic.

6. Nerve Cells
Two types of nerve cells, neurons and glial cells (aka neuroglia cells).
Neurons are communication cells and the functional units of the nervous system.
Neuroglia cells are non-conducting cells that support the nervous system.
We will study two different types of neuroglia; Schwann cells in the PNS and oligodendrocytes in the CNS.

7. Neuroglia or Glial cells
Glia is a Greek word that means glue.
Neuroglial cells support and protect neurons, provide them with nutrients and oxygen, and provide insulation between neurons.
Neuroglial cells are capable of dividing via mitosis and there are 6 different types (4 in the CNS and 2 in the PNS)
Oligodendrocytes - Produce myelin sheath around nerve fibers in the central nervous system
Schwann cells - Form myelin sheath in the peripheral nervous system

8. Gliomas
Gliomas are tumors that develop in the brain involving the glial cells.
Most cases of malignant brain tumors are gliomas.

9. Neurons Neurons are the oldest and longest cells in the human body.
Neurons cannot divide via mitosis but current research suggests that adults can produce new neurons in their brains from neural stem cells.

10. Anatomy of a Neuron (review)
Cell body: Contains the nucleus, rough ER and other organelles. Responsible for the maintenance and daily activities of the cell
Axon: a very long and thin extension of cytoplasm from the cell body. Carries impulses away from the cell body.
Dendrites: much smaller cytoplasm extensions which carry impulses to the cell body (receive information)

11. Anatomy of a Neuron (review)
Myelin Sheath: a type of insulation that is wrapped around the axons of neurons. Helps reduce signal loss.
Schwann Cells: produce the myelin sheath. A created by specialized glial cells wrapping themselves around the axon.
Nodes of Ranvier: gaps between myelin sheath where the axon is “naked”.

12. Anatomy of a Neuron (review)
Neurilemma: a very thin membrane that can be found surrounding the axons of neurons in the PNS. Helps the neurons to regenerate after trauma.
NOTE: Neurons that lack a neurilemma and myelin sheath (grey matter of the brain) do not regenerate, which means trauma to those neurons is permanent.

14. Myelin Sheath on Neurons
Functions:
Saves the neuron energy
Helps neuron maintain itself
Speeds up the transmission of impulses
Helps damaged or severed axons regenerate
In multiple sclerosis the sheaths of myelinated neurons of the CNS become scarred. (pg 414)

15. Sensory Neurons Aka afferent neurons
Pick up and relay information from the external environment to the CNS
Found in clusters, known as ganglia, outside of the CNS.
Ears, eyes, skin, nose, tongue, etc.

16. Motor Neurons Aka efferent neurons.
Carry signals from the CNS to effectors.
Effectors: muscles, organs, glands.
Produce responses such as movement and release of hormones.

17. Interneurons Neurons between neurons.
Located mostly in the spinal cord and brain. (grey matter)
Link sensory and motor neurons to each other
Interpret the messages picked up by sensory neurons

19. Reflexes
Reflex arc: a circuit through the spinal cord consisting of a sensory neuron, interneuron and motor neuron.
Reflex actions are not carried to the brain, instead they are interpreted in the spinal cord.
Reflexes help prevent major injury by reducing the amount of time it takes for the reaction to happen after the sensory input.

21. Reflex Arc Review Five basic components of the reflex arc Receptor
Sensory neuron
Interneuron in spinal cord
Motor neuron
Effector