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Galactose.

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Presentation on theme: "Galactose."— Presentation transcript:

1 Galactose

2 GALACTOSE GALACTOSE METABOLISM

3 GALACTOSE Galactose Galactose-1-phosphate ATP ADP
Galactokinase Galactose Galactose-1-phosphate ATP ADP Galactose-1-phosphate uridyl transferase Galactose-1-p Glucose-1-p + UDP-glucose UDP-galactose

4 GALACTOSE UMP UDP-glucose glucose-1-p glucose-6-p
UDP-galactose UDP-glucose UMP UDP-glucose glucose-1-p glucose-6-p Glucose-6-phosphatase GLUCOSE

5 GALACTOSSEMIA: GALACTOSE
This is a disease related to galactose metabolism. Clinical manifestations include: Prolonged neonatal jaundice mental retardation cataract

6 FRUCTOSE

7 FRUCTOSE ATP Fructose Fructokinase ADP Fructose-1-p Aldolase Dihdroxyacetone + Glyceraldehyde phosphate GLYCOLYTIC PATHWAY

8 FRUCTOSE ATP Glyceraldehyde-3-phosphate ADP Glyceraldehyde ATP ADP Glycerol ATP ATP ADP ADP 2-phosphoglycerate Glycerol-3-phosphate Dihydroxyacetone phosphate

9 Fructose intolerance:
Deficeincy of enzyme Fructose-1-phosphate ALDOLASE. Clinical manifestations include: Hypoglycemia Vomitting hepatomegaly


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